亚太传统医药2026，Vol.22Issue(6)：189-193,5.DOI:10.11954/ytctyy.202606032
基于"生病起于过用"理论探讨代谢相关脂肪性肝病的发病机制
Discussion on the Pathogenesis of Metabolic Associated Fatty Liver Disease:Based on the Theory of"Illness Originates from Overuse"
摘要
Abstract
Metabolic associated fatty liver disease(MAFLD)is the most common chronic liver disease worldwide,with its incidence rate continuously rising.The disease pathology is rather complex,and there are currently no specific thera-peutic drugs available in China.Based on the theory of"illness originates from overuse"in the Huangdi Neijing,the pathogenesis and treatment methods of MAFLD are explored.It is found that the main pathogenesis of MAFLD is characterized by deficiency at the root and excess at the surface,manifested as deficiency of the liver,spleen and kidney,and the interconnection of phlegm and blood stasis.The treatment principle is to soothe the liver,strengthen the spleen,tonify the kidney and consolidate the root,eliminate phlegm and dampness,and remove blood stasis to unblock the meridians.This paper discusses the role of the theory of"illness originates from overuse"in the treatment of MAFLD from the perspective of pathogenesis,providing a new perspective for the prevention and treatment of MAFLD.关键词
代谢相关脂肪性肝病/肝脾肾虚/痰瘀互结/生病起于过用/发病机制Key words
metabolic associated fatty liver disease/deficiency of liver,spleen and kidney/interconnection of phlegm and blood stasis/illness arises from overuse/pathogenesis分类
医药卫生引用本文复制引用
宋思妤,史晓伟..基于"生病起于过用"理论探讨代谢相关脂肪性肝病的发病机制[J].亚太传统医药,2026,22(6):189-193,5.基金项目
国家自然科学基金项目(82360884,82360955) （82360884,82360955）
甘肃省中医药管理局中医药防治重大疾病科研项目(GZKZ-2024-6) （GZKZ-2024-6）
