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Development and validation of a static multiple light scattering(SMLS)method for real-time colloidal stability assessment in nanoparticle formulations

Haiyang Shen Shiqi Huang Renjie Li Hongliang Wang Yanfang Yang Yuling Liu Jun Ye Xiaohai Ma

药物分析学报（英文）2026，Vol.16Issue(3)：708-722,15.

药物分析学报（英文）2026，Vol.16Issue(3)：708-722,15.DOI:10.1016/j.jpha.2025.101396

Development and validation of a static multiple light scattering(SMLS)method for real-time colloidal stability assessment in nanoparticle formulations

Haiyang Shen ¹Shiqi Huang ²Renjie Li ²Hongliang Wang ²Yanfang Yang ²Yuling Liu ²Jun Ye ²Xiaohai Ma³

作者信息

1. Department of Interventional Diagnosis and Treatment,Beijing Anzhen Hospital,Capital Medical University,Beijing,100029,China||Department of Vascular Surgery,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091,China
2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing,100050,China||Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,100050,China
3. Department of Interventional Diagnosis and Treatment,Beijing Anzhen Hospital,Capital Medical University,Beijing,100029,China
折叠

摘要

关键词

Nanoparticle formulations/Colloidal stability/Static multiple light scattering/Dynamic light scattering/Drug delivery

Key words

Nanoparticle formulations/Colloidal stability/Static multiple light scattering/Dynamic light scattering/Drug delivery

引用本文复制引用

Haiyang Shen,Shiqi Huang,Renjie Li,Hongliang Wang,Yanfang Yang,Yuling Liu,Jun Ye,Xiaohai Ma..Development and validation of a static multiple light scattering(SMLS)method for real-time colloidal stability assessment in nanoparticle formulations[J].药物分析学报（英文）,2026,16(3):708-722,15.

基金项目

This work was financially supported by the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sci-ences,China(Grant No.:2021-I2M-1-026),the National Natural Science Foundation of China(Grant No.:82304393),Beijing Natural Science Foundation,China(Grant No.:L242027),and the National Key Research and Development Program of China(Grant No.:2023YFC2706100).Scheme 1,Figs.2A,4A,7A,and 8A and Graphical abstract were drawn by using BioRender.com. （CAMS）

药物分析学报（英文）

ISSN：2095-1779

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