摘要
Abstract
Objective To study the effects of Yiqi Qiyao decoction+short-term intensive insulin therapy on blood glucose fluctuation and insulin resistance in type 2 diabetes mellitus patients.Methods From January 2022 to January 2024,125 patients with type 2 diabetes mellitus enrolled in our hospital were randomized into a control group(n=63)and a study group(n=62)by random number table method.In the control group,patients were treated with short-term intensive insulin therapy.On the basis of the regimen adopted in the control group,patients in the study group were additionally treated with Yiqi Qiyao decoction.The total effective rate,fluctuation of blood glucose index,fluctuation of blood glucose index,insulin resistance,fasting insulin and incidence of adverse reactions were compared between the two groups.Results Compared with the control group(82.54%),the study group achieved a significantly higher total effective rate of treatment(95.16%)(P＜0.05).Both groups presented reductions in fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin after treatment,those indexes were markedly lower in the study group versus the control group(P＜0.05).The average blood glucose and hyperglycemia time of the two groups were lower than those before treatment,and those of the study group were lower than those of the control group(P＜0.05).The insulin resistance index and fasting insulin in the two groups were lower than those before treatment,and those in the study group were smaller than those in the control group(P＜0.05).The incidence of adverse reactions showed no significant difference between the study group and the control group(P＞0.05).Conclusion Yiqi Qiyao decoction and short-term intensive insulin therapy for type 2 diabetes mellitus can effectively control blood glucose fluctuations,improve the total effective rate of treatment,reduce insulin resistance index,and have mild clinical adverse reactions.It is an effective combination of traditional Chinese medicine and Western medicine.关键词
益气芪药汤/短期胰岛素/2 型糖尿病/血糖波动/胰岛素抵抗Key words
Yiqi Qiyao decoction/Short-term insulin/Type 2 diabetes mellitus/Blood glucose fluctuation/Insulin resistance分类
医药卫生
