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紫金龙属生物碱类成分、生源合成途径及药理活性研究进展

李瑞雪 林永强 魏锋 潘英妮 刘晓秋 王献瑞 荆文光 陈佳 杨建波 段宝忠 程显隆

中草药2026,Vol.57Issue(11):4467-4482,16.
中草药2026,Vol.57Issue(11):4467-4482,16.DOI:10.7501/j.issn.0253-2670.2026.11.032

紫金龙属生物碱类成分、生源合成途径及药理活性研究进展

Research progress on alkaloid components in plants from Dactylicapnos and their biosynthetic pathways and pharmacological activities

李瑞雪 1林永强 2魏锋 2潘英妮 1刘晓秋 1王献瑞 2荆文光 2陈佳 2杨建波 2段宝忠 3程显隆2

作者信息

  • 1. 沈阳药科大学中药学院,辽宁沈阳 110016
  • 2. 中国食品药品检定研究院,北京 100050
  • 3. 大理大学药学院,云南大理 671000
  • 折叠

摘要

Abstract

With the continuous deepening of research on active ingredients in traditional Chinese medicine,Dactylicapnos alkaloids play an increasingly important role in the fields of plant chemistry and innovative drug development.This article elaborates on the main achievements and progress in the research of alkaloid components in the Dactylicapnos at home and abroad,and introduces the research status and characteristics of this field at home and abroad.By comparing domestic and foreign studies,this article found that there are some hot and difficult issues in the research field of Dactylicapnos alkaloid components,mainly manifested in the imbalance of alkaloid research among different species in Dactylicapnos,the narrow scope of alkaloid components and pharmacological activity research in this genus.Finally,this article provides a review of the efficacy,chemical composition,biosynthetic pathways,and pharmacological activities of Dactylicapnos,pointing out the shortcomings of current research and proposing future research directions and possible development trends.This article aims to provide reference for researchers on Dactylicapnos alkaloids and provide insights and suggestions for subsequent investigations.

关键词

罂粟科/紫金龙属/生物碱/生物合成途径/异喹啉类生物碱

Key words

Papaveraceae/Dactylicapnos Wall./alkaloids/synthetic pathway/isoquinoline alkaloids

分类

医药卫生

引用本文复制引用

李瑞雪,林永强,魏锋,潘英妮,刘晓秋,王献瑞,荆文光,陈佳,杨建波,段宝忠,程显隆..紫金龙属生物碱类成分、生源合成途径及药理活性研究进展[J].中草药,2026,57(11):4467-4482,16.

基金项目

新疆维吾尔自治区重点研发任务专项(2023B03001-2,2024B02023-2) (2023B03001-2,2024B02023-2)

中草药

0253-2670

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