中国内镜杂志2026，Vol.32Issue(5)：9-18,10.DOI:10.12235/E20250436
Mimics软件引导下TBNA与EBUS-TBNA对肺门及纵隔淋巴结肿大的肺占位性病变的诊断效能比较
摘要
Abstract
Objective To compare the diagnostic efficacy of transbronchial needle aspiration(TBNA)guided by Mimics software and endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)in patients with hilar and mediastinal lymph node enlargement in pulmonary space-occupying lesions.Methods A retrospective analysis was conducted on the clinical data of 136 patients with hilar and mediastinal lymph node enlargement(diameter≥1.5 cm)shown by chest CT in the hospital from January 2019 to May 2024.Sixty-eight patients who underwent Mimics software-guided TBNA were included in the Mimics-TBNA group,and 68 patients who underwent EBUS-TBNA were included in the EBUS-TBNA group.The positive diagnostic rate,operation time,examination cost and complication rate of the two groups were compared.Results Among the 136 patients,86 were ultimately diagnosed with malignant tumors,including 81 with lung cancer and 5 with lymphoma or other metastatic tumors.Additionally,21 patients were diagnosed with benign lesions,29 had inconclusive diagnoses or blood clots on aspiration.In the Mimics software-guided TBNA group,43 patients were diagnosed with malignant tumors(41 with lung cancer and 2 with lymphoma or other metastatic tumors),9 with benign lesions,and 16 had inconclusive diagnoses or blood clots on aspiration.The overall diagnosis positivity rate for lesions was 76.47%(52/68),and the diagnosis positivity rate for malignant tumors was 63.23%(43/68).In the EBUS-TBNA group,43 patients were diagnosed with malignant tumors(40 with lung cancer and 3 with other metastatic tumors),12 with benign lesions,and 13 had inconclusive diagnoses or blood clots on aspiration.The overall diagnosis positivity rate for lesions was 80.88%(55/68),and the diagnosis positivity rate for malignant tumors was 63.23%(43/68).No severe complications were observed in either group.There were no statistically significant differences in the total positive rate of lesion diagnosis,the positive rate of malignant tumor diagnosis and the incidence of severe complications were similar between the two groups of patients(P>0.05).The operation time of the Mimics-TBNA group was shorter than that of the EBUS-TBNA group,and the examination cost was lower than that of the EBUS-TBNA group.The differences were statistically significant(P<0.05).Conclusion Mimics software-guided TBNA can significantly shorten the operation time,reduce examination costs,and have a high positive diagnostic rate and safety.It has high application value in the diagnosis of mediastinal lymph node enlargement.关键词
Mimics软件/经支气管针吸活检(TBNA)/淋巴结肿大/肺占位性病变/三维重建/诊断效能Key words
Mimics software/transbronchial needle aspiration(TBNA)/lymph node enlargement/pulmonary space-occupying lesion/three-dimensional reconstruction/diagnostic efficacy分类
医药卫生引用本文复制引用
龚正,蒋安蓉,龚萍,郑景鸿,陈俊,Aditya Anil..Mimics软件引导下TBNA与EBUS-TBNA对肺门及纵隔淋巴结肿大的肺占位性病变的诊断效能比较[J].中国内镜杂志,2026,32(5):9-18,10.基金项目
宜昌市卫健委科技创新项目(WJ2025Y08) （WJ2025Y08）
