中国内镜杂志2026，Vol.32Issue(5)：59-65,7.DOI:10.12235/E20250416
不同入路胆总管结石腹腔镜手术对患者炎性应激、胃肠功能、血清谷丙转氨酶和总胆红素水平的影响
Effects of different approaches in laparoscopic surgery for calculus of the common bile duct on inflammatory stress,gastrointestinal function and serum GPT and TBiL levels
贾顺虎 1黄坤 2赵攀 2何运胜 2李敬东3
作者信息
- 1. 川北医学院临床医学院,四川 南充 637000
- 2. 绵阳市中医医院 普通外科,四川 绵阳 621000
- 3. 川北医学院附属医院 肝胆外科,四川 南充 637100
- 折叠
摘要
Abstract
Objective To explore the effects of different approaches on inflammatory stress,gastrointestinal function and serum glutamic-pyruvic transaminase(GPT)and total bilirubin(TBiL)levels in patients undergoing laparoscopic surgery for calculus of the common bile duct.Methods From June 2021 to January 2025,75 patients with calculus of the common bile duct admitted to Mianyang Hospital of Traditional Chinese Medicine were selected and divided into group A(n=37)and group B(n=38)according to different approaches.Group A underwent laparoscopic transcystic common bile duct exploration(LTCBDE),while group B underwent laparoscopic common bile duct exploration(LCBDE).The clinical data of the two groups were counted.Results The intraoperative blood loss in group A was less than that in group B,the hospitalization time and maximum diameter of stones in group A were shorter than those in group B,the differences were statistically significant(P<0.05).Three days after operation,the serum levels of C-reactive protein(CRP),procalcitonin(PCT)and white blood cells(WBC)in both groups were significantly increased compared with those before the operation,but those in group A were significantly lower than those in group B,and the differences were statistically significant(P<0.05).The time for the recovery of anal exhaust,the disappearance of bowel sounds and the relief of abdominal pain in group A were significantly shorter than those in group B,and the differences were statistically significant(P<0.05).The serum GPT and TBiL levels 3 days after surgery in both groups were significantly decreased compared with those before the operation,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the total incidence of complications between the two groups of patients(P>0.05).Conclusion LTCBDE and LCBDE have good curative effects on calculus of the common bile duct,and can effectively improve liver function.Among them,LTCBDE is more conducive to the postoperative recovery of patients,reducing inflammatory stress and promoting the recovery of gastrointestinal function.关键词
胆总管结石/腹腔镜/手术/炎性应激/胃肠功能Key words
calculus of the common bile duct/laparoscopy/surgery/inflammatory stress/gastrointestinal function分类
医药卫生引用本文复制引用
贾顺虎,黄坤,赵攀,何运胜,李敬东..不同入路胆总管结石腹腔镜手术对患者炎性应激、胃肠功能、血清谷丙转氨酶和总胆红素水平的影响[J].中国内镜杂志,2026,32(5):59-65,7.
