中国全科医学2026，Vol.29Issue(20)：2753-2758,2774,7.DOI:10.12114/j.issn.1007-9572.2026.0035
成人肥胖的预防与管理:从六大关键词看2025年度进展与趋势
Prevention and Management of Adult Obesity:Progress and Trends from Six Keywords in 2025
摘要
Abstract
In 2025,obesity diagnosis and management entered a new stage characterized by disease stratification and long-term care.Focusing on six key topics:obesity classification,clinical guidelines,novel pharmacotherapies,comorbidity management,weight management clinics,and nutrition labeling,this paper summarizes the major advances in obesity research and practice worldwide in 2025.The Lancet Diabetes and Endocrinology Commission proposed a new framework distinguishing pre-clinical obesity and clinical obesity.American Association of Clinical Endocrinology(AACE),European Association for the Study of Obesity(EASO),and WHO further emphasized that treatment should be determined by obesity-related complications and functional impairment.Tirzepatide,mazdutide,oral GLP-1 receptor agonists,and multi-target agents have propelled anti-obesity medications into an era of high efficacy and diversification.The management of obesity-related comorbidities and diseases,including type 2 diabetes,heart failure with preserved ejection fraction,metabolic dysfunction-associated steatohepatitis,osteoarthritis,and obstructive sleep apnea,has become a clinical priority.China is concurrently advancing the establishment of standardized weight management clinics and the implementation of digital labeling for pre-packaged foods,marking a strategic shift in obesity management from purely clinical treatment toward integrated prevention and care.This paper aims to provide an annual reference for clinical research,specialty development,and practice in the field of obesity for the year 2026.关键词
肥胖管理/肥胖症/诊疗指南/肥胖分型/胰高血糖素样肽1受体激动剂/慢性病共病/体重管理门诊/数字营养标签Key words
Obesity management/Obesity/Diagnostic and treatment guideline/Obesity classification/Glucagon-like peptide-1 receptor agonists/Multiple chronic conditions/Weight management clinics/Digital nutrition labels分类
医药卫生引用本文复制引用
陈向阳,黄红梅,李舍予..成人肥胖的预防与管理:从六大关键词看2025年度进展与趋势[J].中国全科医学,2026,29(20):2753-2758,2774,7.基金项目
国家自然科学基金资助项目(82570964,72342014) （82570964,72342014）
癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项项目(2025ZD0550604) （2025ZD0550604）
成都市科学技术局重点研发支撑计划(2025-YF09-00033-SN) （2025-YF09-00033-SN）
四川大学135高端人才项目(ZYYC24001) （ZYYC24001）
