中国输血杂志2026，Vol.39Issue(5)：610-618,9.DOI:10.13303/j.cjbt.issn.1004-549x.2026.05.006
造血干细胞移植并发胃肠道移植物抗宿主病管理的最佳证据总结
Summary of the best evidence for the management of gastrointestinal graft-versus-host disease after hematopoietic stem cell transplantation
摘要
Abstract
Objective To summarize the best evidence for the management of patients with gastrointestinal graft-versus-host disease after hematopoietic stem cell transplantation,and provide evidence-based references for clinical nursing work.Methods A systematic search was conducted for relevant evidence on the management of patients with gastrointestinal graft-versus-host disease after hematopoietic stem cell transplantation from domestic and foreign databases,as well as web-sites of blood and bone marrow transplantation related societies.The search period was from the establishment of the data-base until February 2026.Results After screening,a total of 19 articles were included,encompassing 3 clinical deci-sions,1 recommended practice,4 guidelines,7 expert consensuses,and 4 evidence summaries.Twenty-five pieces of best evidence were summarized across 8 aspects:multidisciplinary collaboration,influencing factors,assessment and monitoring,diagnostic differentiation,symptom management,dietary nutrition,medication guidance,and health education.Conclusion Summarizing the relevant evidence on the management of patients with gastrointestinal graft-versus-host disease after hem-atopoietic stem cell transplantation can provide evidence-based support for clinical medical staff,and it is recommended to apply it in combination with clinical practice and patient wishes.关键词
造血干细胞移植/移植物抗宿主病/胃肠道/证据总结/循证护理Key words
hematopoietic stem cell transplantation/graft-versus-host disease/gastrointestinal tract/summary of evi-dence/evidence-based nursing分类
医药卫生引用本文复制引用
顾芳臣,葛永芹,梅会娟,陆茵,朱霞明..造血干细胞移植并发胃肠道移植物抗宿主病管理的最佳证据总结[J].中国输血杂志,2026,39(5):610-618,9.基金项目
苏州市科技发展计划(医疗卫生科技创新-应用基础研究)项目(SKJY2021064) （医疗卫生科技创新-应用基础研究）
