中国比较医学杂志2026，Vol.36Issue(10)：72-81,10.DOI:10.3969/j.issn.1671-7856.2026.10.007
基于新兴替代方法的毒理学教学体系重构
Redesigning the toxicology teaching system based on new approach methods
摘要
Abstract
New approach methodologies(NAMs)are emerging as a key direction in the development of international toxicology procedures,gradually driving the shift in toxicity assessment from traditional animal testing toward diverse,non-animal-based technologies.This review considers the global development of NAMs and categorizes their main technical types,including in vitro,in silico,and in chemico approaches,while analyzing their advantages and limitations.It further examines the evolving trends in toxicology education worldwide,highlighting the fact that many universities have incorporated NAMs into their curricula,with a growing emphasis on interdisciplinary integration and hands-on training.Based on the current state of toxicology education in China,this study proposes several recommendations to support modernization,including strengthening curriculum development in terms of NAMs,promoting interdisciplinary teaching models,incorporating remote and virtual experimental platforms,and enhancing faculty training and educational resources.关键词
新兴替代方法/毒理学/课程体系建设/微生理系统/类器官/人工智能Key words
new approach methodologies(NAMs)/toxicology/curriculum development/micro-physiological systems/organoids/artificial intelligence分类
医药卫生引用本文复制引用
叶海绿,赵韫琦..基于新兴替代方法的毒理学教学体系重构[J].中国比较医学杂志,2026,36(10):72-81,10.基金项目
浙江省教育厅本科省级教学改革项目(JGCG2025308) （JGCG2025308）
浙江省自然科学基金(ZCLTGY24C1001). （ZCLTGY24C1001）
