中国医院用药评价与分析2026，Vol.26Issue(5)：631-634,4.DOI:10.14009/j.issn.1672-2124.2026.05.025
通关藤注射液致不良反应文献分析
Literature Analysis of Adverse Drug Reactions Induced by Tongguanteng Injection
摘要
Abstract
OBJECTIVE:To investigate the clinical characteristics,leading factors and countermeasures of adverse drug reactions(ADR)induced by Tongguanteng injection,and to provide references for improving clinical medication safety.METHODS:Case reports on ADR induced by Tongguanteng injection from database establishment to Aug.2025 were collected by retrieving CNKI,Wanfang,VIP,PubMed,Web of Science and EMbase databases,descriptive analysis was conducted on relevant data.RESULTS:A total of 8 studies related to ADR induced by Tongguanteng injection were retrieved,including 22 patients,with a male-to-female ratio of 1∶1.Most patients were aged≥50 years.ADR mostly occurred within 1 h after administration,severe cases included anaphylactic shock(1 case),anaphylactoid reaction(1 case),severe adverse drug reactions(2 cases),the rest were mild ADR such as chest distress,dyspnea and diarrhea.A total of 10 new ADR not recorded in drug instructions were detected,including 2 cases of increased heart rate,2 cases of tachycardia,1 case of precordial stabbing pain,1 case of arrhythmia,1 case of skin edema,1 case of anaphylactoid-like reaction,1 case of eye tearing,and 1 case of eye redness and swelling,accounting for 15.9%,which had supplemented the ADR monitoring data of the drug.CONCLUSIONS:Clinicians should pay close attention to ADR induced by Tongguanteng injection,and strengthen medication monitoring to ensure medication safety.关键词
通关藤注射液/消癌平注射液/药品不良反应/抗肿瘤/文献分析Key words
Tongguanteng injection/Xiaoaiping injection/Adverse drug reactions/Antitumor/Literature analysis分类
医药卫生引用本文复制引用
姜荣荣,杭永付,袁芳..通关藤注射液致不良反应文献分析[J].中国医院用药评价与分析,2026,26(5):631-634,4.基金项目
江苏省省级中医重点专科(肝病科)(No.苏中医医政[2023]5号) （肝病科）
