中华临床免疫和变态反应杂志2026，Vol.20Issue(2)：91-97,7.DOI:10.3969/j.issn.1673-8705.2026.02.003
生物制剂在IgG4相关性疾病治疗中的应用进展
The application of biologic agents in the treatment of IgG4-related diseases
刘月 1朱翰斌 2孙力祺 3张德宇 2黄浩杰 2邹晓平1
作者信息
- 1. 210093 南京,南京大学医学院附属泰康仙林鼓楼医院消化内科
- 2. 200433 上海,海军军医大学(第二军医大学)长海医院消化科
- 3. 313000 浙江 陆军第七十二集团军医院消化内科
- 折叠
摘要
Abstract
IgG4-related disease(IgG4-RD)is a chronic autoimmune condition of unclear etiology,characterized by significantly elevated serum IgG4 levels,and often accompanied by extensive infiltration of lymphocytes and IgG4-positive plasma cells,as well as fibrosis,in affected tissues and organs.Compared with traditional steroid therapy,biologic agents offer advantages,such as greater treatment specificity,improved safety and efficacy,and less side effects.However,the use of biologic agents in the treatment of IgG4-RD re-mains in the exploratory stage.This article summarizes and analyzes the mechanisms of action and clinical effi-cacy of biologic agents in IgG4-RD.关键词
生物制剂/IgG4相关性疾病Key words
biologic agents/IgG4-related diseases引用本文复制引用
刘月,朱翰斌,孙力祺,张德宇,黄浩杰,邹晓平..生物制剂在IgG4相关性疾病治疗中的应用进展[J].中华临床免疫和变态反应杂志,2026,20(2):91-97,7.
