中华临床免疫和变态反应杂志2026，Vol.20Issue(2)：103-114,12.DOI:10.3969/j.issn.1673-8705.2026.02.005
嵌合抗原受体T细胞及其衍生疗法在自身免疫病中的应用进展
Progress in the application of chimeric antigen receptor T cell therapy in autoimmune diseases
摘要
Abstract
Chimeric antigen receptor T(CAR-T)cell therapy has become a revolutionary approach in tumor immunotherapy.In recent years,CAR therapy has shown therapeutic potential in the treatment of autoim-mune diseases.This article introduces the application of CAR-T and CAR-related therapies in autoimmune dis-eases,emphasizing that improving the safety,efficacy,durability,and cost reduction of CAR-T therapy is an important goal for future research.关键词
嵌合抗原受体T细胞/自身免疫病/免疫治疗Key words
chimeric antigen receptor T/autoimmune diseases/immunotherapy引用本文复制引用
陈明,刘丽荣,林进,曹恒..嵌合抗原受体T细胞及其衍生疗法在自身免疫病中的应用进展[J].中华临床免疫和变态反应杂志,2026,20(2):103-114,12.基金项目
浙江省自然科学基金重点项目(LHDMZ23H310001) Key Project of Zhejiang Provincial Natural Science Foundation(LHDMZ23H310001) （LHDMZ23H310001）
