波谱学杂志2026，Vol.43Issue(2)：214-222,9.DOI:10.11938/cjmr20253180
磁共振成像技术在轻度创伤性脑损伤诊断与预后中的应用
Advances in Magnetic Resonance Imaging for the Diagnosis and Prognosis of Mild Traumatic Brain Injury
摘要
Abstract
Mild traumatic brain injury(mTBI)is a common neurological disorder in clinical practice,yet its diagnosis and management remain challenging due to the hidden nature of symptoms and the underlying pathological complexity.While imaging techniques such as computed tomography(CT)and conventional magnetic resonance imaging(MRI)are the mainstay for acute-phase assessment,they have limitations in detecting subtle injuries and evaluating long-term prognosis.In recent years,multimodal MRI technology has been developed in the research of mTBI,offering novel approaches for revealing its potential pathological mechanisms and exploring the key objective imaging indicators.Specifically,susceptibility weighted imaging(SWI)is sensitive for detecting microbleeds and iron deposition in the brain;amide proton transfer(APT)imaging reflects changes in molecular and metabolic levels;diffusion and functional imaging techniques help depict abnormalities in white matter microstructure and brain networks.The integration of multimodal MRI and the construction of imaging databases will be important directions for advancing early diagnosis,precise assessment,and AI-assisted intervention.This article systematically reviews research progress of related MRI techniques,analyzes their advantages and limitations,and discusses their prospects in clinical translation.关键词
轻度创伤性脑损伤/磁共振成像/磁敏感加权成像/弥散张量成像/功能磁共振成像Key words
mild traumatic brain injury(mTBI)/magnetic resonance imaging(MRI)/susceptibility-weighted imaging(SWI)/diffusion tensor imaging(DTI)/functional MRI分类
数理科学引用本文复制引用
傅芬芳,林国兵,李梅芳..磁共振成像技术在轻度创伤性脑损伤诊断与预后中的应用[J].波谱学杂志,2026,43(2):214-222,9.基金项目
福建省自然科学基金计划项目(2023J011722). （2023J011722）
