动物医学进展2026，Vol.47Issue(6)：70-77,8.
2株鸡源多杀性巴氏杆菌分离株与疫苗株生物学特性比较分析
Comparative Analysis of Biological Characteristics between Two Chicken-derived Pasteurella multocida Isolates and Vaccine Strain
摘要
Abstract
To understand the differences in the biological characteristics of avian Pasteurella multocida in different regions,PCR detection,drug sensitivity test,biochemical identification,and biofilm formation ability test were con-ducted on 3 strains of avian Pasteurella multocida.The results showed that all three strains of Pasteurella multocida were podoconiosis serotype A.All contained exbB,exbD,hgbA,hgbB,tonB,fur,fimA,hsf2,ptfA,pfhA,tadD,oma87、ompA、ompH、plpB、psl、plpE、sodA,sodC,nanB,pmHAS 21 virulence genes,the virulence gene tbpA is contained only in Pm1,all contain the aminoglycoside resistance genes rpsE,rpssL,rrss.Pm1 strain showed resist-ance to cephalexin,tetracycline,lincomycin,clindamycin and vancomycin,Pm2 strain showed resistance to lincomy-cin,clindamycin and vancomycin,and Pm3 strain showed resistance to five antibiotics,including streptomycin,madicillin,lincomycin,clindamycin,and vancomycin.The Pm1 strain was able to form a bioepidermal membrane,while the Pm2,Pm3 strains were barely able to form biofilm.The biological characterisation of three strains of Pas-teurella multocida revealed its virulence genes,drug resistance and biofilm-forming ability,which is of great signifi-cance for the study of pathogenicity and clinical control.关键词
禽多杀性巴氏杆菌/毒力基因/耐药基因/药敏试验/生物被膜Key words
Pasteurella multocida/Virulence genes/Resistance genes/Drug sensitivity test/Biofilm formation capacity test分类
农业科技引用本文复制引用
祝成才,陈鹏旭,王泽凯,张留君,赵磊,闫康,贺绍君..2株鸡源多杀性巴氏杆菌分离株与疫苗株生物学特性比较分析[J].动物医学进展,2026,47(6):70-77,8.基金项目
校企合作项目(横20240360) （横20240360）
校企合作项目(横20240327) （横20240327）
校企合作项目(横20240715) （横20240715）
