黑龙江畜牧兽医Issue(6):24-29,6.DOI:10.13881/j.cnki.hljxmsy.2025.11.0028
粪菌移植调控猪肠道微生物的作用机制及在生产中的应用研究进展
Research progress on the mechanisms of fecal microbiota transplantation in modulating porcine gut microbiota and its application in production
摘要
Abstract
As a crucial microbiome intervention strategy,fecal microbiota transplantation(FMT)demonstrates significant potential in modulating the composition and function of porcine gut microbiota.FMT plays a key role in preventing and controlling post-weaning diarrhea,improving growth performance,and enhancing meat quality via multiple pathways,including reshaping the gut microbial community structure,regulating intestinal metabolic profiles,enhancing intestinal barrier integrity,and modulating host immune responses.Although current FMT technology still faces challenges such as insufficient standardization and unverified long-term safety,with the continuous advancement of microbiome technologies,FMT holds broad prospects for application in livestock production.Therefore,a thorough understanding and precise application of FMT hold the potential to drive innovative developments in pig health management and precision breeding from a microbial perspective.This paper systematically reviewed the mechanisms through which FMT influences porcine gut microbiota and the research progress of its application in swine production.Additionally,the application value of porcine-derived FMT in constructing xenotransplantation models was discussed,aiming to offer a new strategic direction for enhancing sustainability of livestock production.关键词
粪菌移植/猪/肠道微生物/微生物调控/作用机制/肠道健康/生产性能Key words
fecal microbiota transplantation/pig/gut microbiota/microbial regulation/mechanism of action/intestinal health/production performance分类
农业科技引用本文复制引用
赵郑歌,张慢玉,姜辉,邓飞龙,柴建民,李英..粪菌移植调控猪肠道微生物的作用机制及在生产中的应用研究进展[J].黑龙江畜牧兽医,2026,(6):24-29,6.基金项目
国家重点研发计划专项(2023YFE0124400) (2023YFE0124400)