南京医科大学学报（自然科学版）2026，Vol.46Issue(6)：885-893,9.DOI:10.7655/NYDXBNSN260412
婴儿期条栅视力与3岁神经发育的前瞻性队列研究
Association between infant visual acuity and neurodevelopment at three years of age:a prospective cohort study
摘要
Abstract
Objective:To explore the association between infant visual acuity and neurodevelopment at 3 years of age.Methods:We employed a prospective cohort study design.A total of 1 122 children from 1 096 families enrolled in the Jiangsu Birth Cohort between August 2016 and June 2019 were included.At 1 year of age,visual acuity was measured using the Teller Acuity Card Ⅱ.At 3 years of age,neurodevelopmental status was assessed using the Bayley Scales of Infant and Toddler Development,Version Ⅲ Screening Test,covering five domains:cognition,receptive communication,expressive communication,fine motor,and gross motor.Poisson regression models were used to examine the associations between infant visual acuity and neurodevelopment at 3 years of age.Results:Among the 1 122 children,94(8.4%)showed abnormal visual acuity.The prevalence of noncompetent neurodevelopment across five domains ranged from 3.5%to 10.3%.Compared with the group with normal visual acuity in infancy,the group with abnormal visual acuity had a 96%increased risk of being noncompetent development in gross motor domain at age 3(RR=1.96,95%CI 1.03-3.70).This association remained stable after excluding twins,preterm infants,low birth weight infantsand children conceived via assisted reproductive technology.Conclusion:Abnormal visual acuity in infancy was associated with an increased risk of being noncompetent in gross motor development at 3 years of age.关键词
条栅视力/神经发育/认知/语言理解/语言表达/精细运动/大运动Key words
visual acuity/neurodevelopment/cognitive/receptive communication/expressive communication/fine motor/gross motor分类
医药卫生引用本文复制引用
屈越,蒋梦婷,吕红,蒋杨倩,蒋涛,林苑,杜江波,李煚..婴儿期条栅视力与3岁神经发育的前瞻性队列研究[J].南京医科大学学报（自然科学版）,2026,46(6):885-893,9.基金项目
国家自然科学基金(82473651,U24A20748,82574115) （82473651,U24A20748,82574115）
