内科理论与实践2026，Vol.21Issue(2)：167-170,4.DOI:10.16138/j.1673-6087.2026.02.10
慢性Q热合并肾功能不全1例
A case of chronic Q fever complicated with renal insufficiency
摘要
Abstract
Chronic Q fever is caused by Coxiella burnetii infection.There are few clinical cases of chronic Q fever,and cases complicated with renal insufficiency are even more rarely reported.At present,there are few reports about this disease both domestically and internationally,and its clinical characteristics and pathogenesis remain unclear.This article reports a case of a chronic Q fever patient with clinical manifestations of nephrotic syndrome and impaired renal function,whose renal biopsy revealed membranoproliferative glomerulonephritis.After treatment with glucocorticoid,cyclophosphamide,hydroxychloroquine combined with doxycycline,the patient's renal function improved.关键词
慢性Q热/肾病综合征/膜增生性肾小球肾炎/二代测序/多西环素/羟氯喹Key words
chronic Q fever/nephrotic syndrome/membranoproliferative glomerulonephritis/next-generation sequencing/doxycycline/hydroxychloroquine分类
医药卫生引用本文复制引用
李一林,张春丽,沈平雁,徐静,胡晓帆,李娅..慢性Q热合并肾功能不全1例[J].内科理论与实践,2026,21(2):167-170,4.基金项目
瑞金医院广慈创新技术启航计划(GCQH2025143) （GCQH2025143）
