日用化学品科学2026，Vol.49Issue(6)：28-32,5.DOI:10.3969/j.issn.1006-7264.2026.06.005
龙胆提取物在化妆品中的应用功效评价
Evaluation of the efficacy of gentian extract in cosmetics
莫思琪 1张秋红 1梁子娴 1牛强1
作者信息
- 1. 广东悠质检测技术有限公司,广东 广州 510450
- 折叠
摘要
Abstract
The efficacy of gentian extract in cosmetics by establishing skin barrier damage and inflammation models was evaluated,combined with human efficacy tests and in vitro cell experiments.The effects of gentian extract on stratum corneum hydration,trans-epidermal water loss(TEWL),skin erythema,and the release of inflammatory mediators were systematically investigated.The results demonstrated that gentian extract significantly enhanced skin hydration,repaired impaired skin barrier function,and effectively inhibited the production of the inflammatory cytokine IL-6.The safety of gentian extract was further evaluated using human skin occlusive patch tests and the hen's egg chorioallantoic membrane(HET-CAM)assay,which indicated good skin tolerance and low irritation potential.This study provides a scientific basis for the broader application of gentian extract in cosmetics and supports its further technological development in the skincare field.关键词
龙胆提取物/化妆品/安全性评价/人体测试/体外测试Key words
gentian extract/cosmetics/safety evaluation/human testing/in vitro test分类
化学化工引用本文复制引用
莫思琪,张秋红,梁子娴,牛强..龙胆提取物在化妆品中的应用功效评价[J].日用化学品科学,2026,49(6):28-32,5.
