数字中医药(英文)2026,Vol.9Issue(2):223-240,18.DOI:10.1016/j.dcmed.2026.05.004
人工智能辅助舌诊的可视化分析与临床可解释性评价
Visualization analysis and clinical interpretability evaluation of artificial intelligence-assisted tongue diagnosis
摘要
Abstract
Objective To map the research landscape of artificial intelligence(AI)-assisted tongue diag-nosis through bibliometric analysis and to quantify its diagnostic accuracy and clinical inter-pretability through a diagnostic test accuracy(DTA)meta-analysis. Methods For the bibliometric analysis,the Web of Science Core Collection(WoSCC)was queried for English-language articles and reviews on AI-assisted tongue diagnosis published between January 1,2014 and December 31,2025,and analysed using Bibliometrix,VOSview-er,and CiteSpace,with major output dimensions including annual publication output and disciplinary distribution,journal and citation characteristics,country/region and institution-al collaboration,author networks,keyword co-occurrence,and keyword burst detection.For the DTA meta-analysis,four databases[Scopus,PubMed,Web of Science,and China Nation-al Knowledge Infrastructure(CNKI)]were searched in accordance with the Preferred Report-ing Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy(PRISMA-DTA)guidelines.A bivariate random-effects model hierarchical summary receiver operating characteristic(HSROC)was used to pool sensitivity and specificity,with subgroup analyses by disease category,AI model architecture,and sample-size strata.Methodological quality was assessed with the Quality Assessment of Diagnostic Accuracy Studies version 2(QUADAS-2)tool,and publication bias was evaluated by Deeks'funnel plot asymmetry test. Results A total of 198 publications met the bibliometric eligibility criteria.Annual output in-creased 24.5-fold(from 2 in 2014 to 49 in 2025),with the period 2022-2025 alone accounting for 65.2%of all publications.China contributed approximately 83.5%of all institutional affilia-tions,with Shanghai University of Traditional Chinese Medicine and Jiatuo Xu being the most productive institution and author,respectively.Keyword analysis identified four thematic clusters(AI and deep-learning architectures,image processing and segmentation,traditional Chinese medicine(TCM)-specific applications,and disease-specific applications)and a tem-poral evolution from traditional machine learning to deep learning and transformer-based,explainable,and multimodal AI architectures.Sixteen DTA meta-analysis studies(14 755 participants)covering metabolic and hepatic disorders,oncological and oral lesions,cardiovascular risk,diabetes,and other clinical applications were included in the DTA meta-analysis.The pooled sensitivity was 90.3%[95%confidence interval(CI):86.7%-93.1%]and the pooled specificity was 93.0%(95%CI:90.6%-94.7%);the area under the summary receiv-er operating characteristic(SROC)curve(AUC)was 0.961.Heterogeneity was substantial(I2=95.8%for sensitivity;I2=92.1%for specificity).Subgroup performance was broadly consistent across disease categories,AI architectures,and sample-size strata,and Deeks'test indicated no significant publication bias(P=0.258). Conclusion AI-assisted tongue diagnosis has progressed rapidly and shows pooled diagnos-tic performance comparable to established screening modalities,supporting its potential as a complementary and easily accessible decision-support tool.关键词
舌诊/人工智能/中医/诊断准确性/文献计量学/meta 分析Key words
Tongue diagnosis/Artificial intelligence/Traditional Chinese medicine/Diagnostic accuracy/Bibliometric analysis/Meta-analysis引用本文复制引用
刘梨会,胡凯文,周亚娜..人工智能辅助舌诊的可视化分析与临床可解释性评价[J].数字中医药(英文),2026,9(2):223-240,18.基金项目
Hubei Provincial Science and Technology Plan Project(2025CCB018). (2025CCB018)