刑事技术2026，Vol.51Issue(3)：239-245,7.DOI:10.16467/j.1008-3650.2025.0021
电子烟油中丙帕酯和异丙帕酯的质谱鉴定分析
Identification of Propoxate and Isopropoxate in the Seized Electronic Cigarette Oil by Mass Spectrometry
摘要
Abstract
In this study,the methods for the identification of propoxate and isopropoxate in seized e-cigarette oil by gas chromatography-mass spectrometry(GC-MS)and ultra performance liquid chromatography-quadrupole/orbitrap high resolution mass spectrometry(UPLC-Q/Orbitrap HRMS)were established.Based on established methods,two unknown components were identified as propoxate and isopropoxate through structural analysis by MS and the characteristic fragment ions information acquired by EI-MS and Full MS/dd MS2 were similar to the known etomidate.The detection limits of propoxate and isopropoxate were both 0.1μg/mL for GC-MS and 0.1ng/mL for UPLC-Q/Orbitrap HRMS.This method provides a quick and simple approach for the identification of new carboxylate drugs with imidazole ring in the absence of standard substances and it could be applied to the analysis of actual cases.关键词
丙帕酯/异丙帕酯/电子烟油/气相色谱-质谱法/高效液相色谱-高分辨质谱法/裂解机制Key words
propoxate/isopropoxate/electronic cigarette oil/GC-MS/UPLC-HRMS/fragmentation pathways分类
社会科学引用本文复制引用
林葭,曾文灿,林坚,叶树海,庄顺,黄建春..电子烟油中丙帕酯和异丙帕酯的质谱鉴定分析[J].刑事技术,2026,51(3):239-245,7.基金项目
福建省科技兴警科研专项(2024Y0071) （2024Y0071）
