眼科新进展2026，Vol.46Issue(6)：464-467,4.DOI:10.13389/j.cnki.rao.2026.0083
白内障患者术后晶状体后囊膜混浊发生风险的列线图预测模型构建
Construction of a nomogram prediction model for the risk of posterior capsu-lar opacification after cataract surgery
摘要
Abstract
Objective To construct a nomogram prediction model for the risk of posterior capsular opacification(PCO)after cataract surgery.Methods Totally 364 cataract patients who underwent surgery at our hospital between Jan-uary 2022 and June 2023 were enrolled.Patients were followed up for 2 years postoperatively and divided into the PCO group(n=61)and non-PCO group(n=303)based on PCO occurrence.Lasso-Logistic regression was used to screen pre-dictive variables,construct a nomogram model,and assess its predictive performance.Results The incidence of postoper-ative PCO in the 364 patients was 16.76％(61/364).Lasso-Logistic regression analysis revealed that high myopia(OR=2.844,P=0.002),concomitant diabetes mellitus(OR=2.564,P=0.004),glaucoma(OR=2.588,P=0.029),hydrophilic in-traocular lens implantation(OR=3.595,P＜0.001),and no posterior capsular polishing(OR=2.690,P=0.002)were inde-pendent risk factors for postoperative PCO.The nomogram model constructed based on these five indicators yielded an area under the receiver operating characteristic curve of 0.759(95％CI:0.696-0.822).The calibration curve had a slope close to 1,and the Hosmer-Lemeshow goodness-of-fit test showedx2=7.140,P=0.308.Conclusion High myopia,concomitant diabetes mellitus,glaucoma,hydrophilic intraocular lens implantation,and no posterior capsular polishing are independent risk factors for postoperative PCO after cataract surgery.The nomogram prediction model developed using these indicators has good predictive performance and facilitates early identification and individualized intervention of PCO.关键词
白内障/晶状体后囊膜混浊/影响因素/预测模型/列线图Key words
cataract/posterior capsular opacification/influencing factors/prediction model/nomogram分类
医药卫生引用本文复制引用
班景飞,吕靖,刘晓敏,段媛媛,李景珂..白内障患者术后晶状体后囊膜混浊发生风险的列线图预测模型构建[J].眼科新进展,2026,46(6):464-467,4.基金项目
邯郸市科学技术研究与发展计划项目(编号:22422083097ZC) （编号:22422083097ZC）
