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首页|期刊导航|云南民族大学学报(自然科学版)|不同来源沉香精油GC-MS/MS分析及抗氧化研究

不同来源沉香精油GC-MS/MS分析及抗氧化研究

沈远乐 石小秀 党晖 苏丽萍 韦科录 刘振杰 奉建芳

云南民族大学学报(自然科学版)2026,Vol.35Issue(3):363-370,8.
云南民族大学学报(自然科学版)2026,Vol.35Issue(3):363-370,8.DOI:10.3969/j.issn.1672-8513.2026.03.009

不同来源沉香精油GC-MS/MS分析及抗氧化研究

GC-MS/MS analysis and antioxidant activity study of agarwood essential oil from different sources

沈远乐 1石小秀 1党晖 2苏丽萍 1韦科录 1刘振杰 3奉建芳3

作者信息

  • 1. 广西中医药大学药学院,广西南宁 530200
  • 2. 广西中医药大学百年乐制药有限公司,广西南宁 530023
  • 3. 广西中医药大学药学院,广西南宁 530200||广西优势中成药与民族药开发工程技术研究中心,广西南宁 530200
  • 折叠

摘要

Abstract

This study aims to screen the antioxidant active substances in agarwood essential oil,improve quality evaluation standards,and optimize extraction processes.Gas chromatography-tandem mass spectrometry(GC-MS/MS)was employed to compare the effects of different producing origins and extraction methods on its chemical components and to evaluate its antioxidant capacity.The DPPH free radical scavenging rate and total reducing power of 13 batches of essential oils were determined,and quality differential markers were screened by combining grey relational analysis and partial least squares discriminant analysis(PLS-DA).The results showed that all batches except S1,S12,and S13 contained antioxidant 2246,namely 2,2'-methylenebis(4-methyl-6-tert-butylphenol),with mass fractions ranging from 0.15%to 5.35%.S7 exhibited the strongest DPPH scavenging ability,and the mass fraction of its key component,2-methoxy-3-(2-propenyl)phenol,was as high as 75.10%.The PLS-DA model(VIP>1)identified three quality differential markers as potential antioxidant substances:2-(2-phenylethyl)chromone,2-(4-methoxyphenethyl)-4H-chromen-4-one,and 2-methoxy-3-(2-propenyl)phenol.

关键词

沉香/精油/GC-MS/MS/挥发性成分分析/抗氧化活性

Key words

Aquilaria sinensis/essential oil/GC-MS/MS/volatile component analysis/antioxidant activity

分类

医药卫生

引用本文复制引用

沈远乐,石小秀,党晖,苏丽萍,韦科录,刘振杰,奉建芳..不同来源沉香精油GC-MS/MS分析及抗氧化研究[J].云南民族大学学报(自然科学版),2026,35(3):363-370,8.

基金项目

国家自然科学基金(82374044、81860711) (82374044、81860711)

国家重点研发计划(2019YFC1712304). (2019YFC1712304)

云南民族大学学报(自然科学版)

1672-8513

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