The expression of CD39 on NK cells relates to poor HIV-1 suppression in treatment-naïve HIV-1-infected individuals:Association with elevated IL-10 secretion and TIGIT co-expression
Xin Zhang Zhenglai Ma Tong Zhang Hao Wu Bin Su Qianqian Xu Junyan Jin Hongxia Yan Xiaofan Lu Zhen Li Zhiying Liu Rui Wang Lin Yuan
The expression of CD39 on NK cells relates to poor HIV-1 suppression in treatment-naïve HIV-1-infected individuals:Association with elevated IL-10 secretion and TIGIT co-expression
The expression of CD39 on NK cells relates to poor HIV-1 suppression in treatment-naïve HIV-1-infected individuals:Association with elevated IL-10 secretion and TIGIT co-expression
摘要
关键词
HIV-1 infection/Natural killer cells(NK cells)/CD39/IL-10/T-cell immunoreceptor with Ig and ITIM domain(TIGIT)Key words
HIV-1 infection/Natural killer cells(NK cells)/CD39/IL-10/T-cell immunoreceptor with Ig and ITIM domain(TIGIT)引用本文复制引用
Xin Zhang,Zhenglai Ma,Tong Zhang,Hao Wu,Bin Su,Qianqian Xu,Junyan Jin,Hongxia Yan,Xiaofan Lu,Zhen Li,Zhiying Liu,Rui Wang,Lin Yuan..The expression of CD39 on NK cells relates to poor HIV-1 suppression in treatment-naïve HIV-1-infected individuals:Association with elevated IL-10 secretion and TIGIT co-expression[J].中国病毒学,2026,41(2):293-302,10.基金项目
This work was supported by the National Natural Science Foundation of China(NSFC,82472266 to B.S.,82272319 to H.W.),the National Key R&D Program of China(2023YFE0116000,2023YFC2308300,2023YFC2308302 to B.S.),the Beijing High-Level Innovation and Entrepreneurship Talent Support Program-Leading Talent Projects(G202512065 to B.S.),the Public Health Talent Training and Support Program of the National Disease Control and Prevention Administration(B.S.),the Scientific Research Project of Beijing Youan Hospital-CCMU 2022(BJYAYY-YN2022-18 to X.Z.),and the Beijing Key Laboratory for HIV/AIDS Research(BZ0089 to B.S.).The funders had no role in study design,data collection and analysis,decision to publish,or preparation of the manuscript. (NSFC,82472266 to B.S.,82272319 to H.W.)