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首页|期刊导航|中国病毒学|STING1 negatively regulates translation and replication of foot-and-mouth disease virus independently of interferon and is antagonized by the viral proteins 3C and 2B

STING1 negatively regulates translation and replication of foot-and-mouth disease virus independently of interferon and is antagonized by the viral proteins 3C and 2B

Wenhua Shao Zongsheng Zhao Fan Yang Zixiang Zhu Haixue Zheng Wei Zhang Zhitong Chen Tingting Zhou Xiaoyi Zhao Hongyi Liu Chuangwei Chen Xingyan Dong Weijun Cao

中国病毒学2026，Vol.41Issue(2)：355-370,16.
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中国病毒学2026，Vol.41Issue(2)：355-370,16.DOI:10.1016/j.virs.2026.04.007

STING1 negatively regulates translation and replication of foot-and-mouth disease virus independently of interferon and is antagonized by the viral proteins 3C and 2B

STING1 negatively regulates translation and replication of foot-and-mouth disease virus independently of interferon and is antagonized by the viral proteins 3C and 2B

Wenhua Shao 1Zongsheng Zhao 2Fan Yang 3Zixiang Zhu 3Haixue Zheng 3Wei Zhang 3Zhitong Chen 3Tingting Zhou 3Xiaoyi Zhao 3Hongyi Liu 3Chuangwei Chen 3Xingyan Dong 3Weijun Cao3

作者信息

  • 1. College of Animal Science and Technology,Shihezi University,Shihezi 832001,China||State Key Laboratory of Animal Disease Control and Prevention,College of Veterinary Medicine,Lanzhou University,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730000,China
  • 2. College of Animal Science and Technology,Shihezi University,Shihezi 832001,China
  • 3. State Key Laboratory of Animal Disease Control and Prevention,College of Veterinary Medicine,Lanzhou University,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou 730000,China
  • 折叠

摘要

关键词

Foot-and-mouth disease virus(FMDV)/STING1/3C protease/Interferon-independent/Antiviral activity

Key words

Foot-and-mouth disease virus(FMDV)/STING1/3C protease/Interferon-independent/Antiviral activity

引用本文复制引用

Wenhua Shao,Zongsheng Zhao,Fan Yang,Zixiang Zhu,Haixue Zheng,Wei Zhang,Zhitong Chen,Tingting Zhou,Xiaoyi Zhao,Hongyi Liu,Chuangwei Chen,Xingyan Dong,Weijun Cao..STING1 negatively regulates translation and replication of foot-and-mouth disease virus independently of interferon and is antagonized by the viral proteins 3C and 2B[J].中国病毒学,2026,41(2):355-370,16.

基金项目

We thank our laboratory members who helped us improve the manuscript with their technical assistance and invaluable suggestions.This work was supported by the National Key Research and Develop-ment Program of China(No.2021YFD1800300 to FY),the National Natural Science Foundation of China of China(32473064 to WZ),the Fundamental Research Funds for the Central Universities,the Scientific Funds of Gansu Province(23JRRA547 to WJC),the Science and Tech-nology Major Project of Gansu Province(No.22ZD6NA001 to HXZ),the Joint Research Foundation of Gansu Province(No.25JRRA1088,24JRRA804,No.24JRRA813 to FY),the Gansu Province Research-Production Integration Technology Breakthrough Empowerment Plan(25FNNA002 to HXZ),the Earmarked Fund(CARS-35 to HXZ),and the Strategic Priority Research Program of the National Center of Technol-ogy Innovation for Pigs(No.NCTIP-XD/C03 to HXZ).The funders had no role in study design,data collection and analysis,decision to publish,or preparation of the manuscript. （No.2021YFD1800300 to FY）

中国病毒学

1003-5125

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