中国动物检疫2026，Vol.43Issue(5)：15-20,6.DOI:10.3969/j.issn.1005-944X.2026.05.003
2022-2024年四川省眉山市病死猪圆环病毒感染及猪群免疫效果调查
Investigation on Porcine Circovirus Infection in Dead Pigs and Immune Effects in Pig Populations in Meishan City,Sichuan Province from 2022 to 2024
摘要
Abstract
In order to investigate the infection status of porcine circovirus(PCV)in dead pigs and the immune effects in vaccinated pig populations in Meishan City,Sichuan Province,pooled oronasal swab samples were collected from dead pigs on 722 farms/smallholders in 7 districts/counties in the city from 2022 to 2024,for nucleic acid detection of PCV2,PCV3 and PCV4 using fluorescent PCR kits,followed by statistical analysis by year,time period,geographical region and co-infection.Meanwhile,1 080 serum samples were collected from vaccinated pigs on 72 farms/smallholders from 2023 to 2024,to detect PCV2 antibodies using ELISA kits.The results showed that,for the period from 2022 to 2024,the average annual detection rates of PCV2 and PCV3 were 64.82％and 24.52％,respectively,but that of PCV4 was zero;the detection rates of PCV2(65.99％,74.25％)and PCV3(29.63％,33.53％)during the periods from June to September and from October to December were significantly different(P＜0.05)from those from January to May(57.36％,12.79％);the detection rate of PCV2 was slightly different(P＞0.05)between plain valley areas(62.50％)and mountainous/hilly areas(66.22％),but that of PCV3(29.78％,21.33％)was obviously different(P＜0.05);the detection rates of PCV2+PCV3 co-infection in 2023 and 2024(19.28％,23.55％),as well as those during the periods from June to September and from October to December(22.90％,29.94％),were found to be significantly different(P＜0.05)compared with those in 2022(12.55％)and during the January-to-May period(6.20％),respectively.The average annual PCV2 antibody positivity rates in 2023 and 2024 were 86.85％and 85.56％,respectively,with no significant difference(P＞0.05).In conclusion,PCV2 infection was widely distributed and severe in dead pigs in Meishan City,indicating a trend of co-infection with PCV3,especially in the period from June to December,and serious for PCV3 infection in plain valley areas;and current corresponding vaccines failed to completely fight against PCV2 infection.Therefore,vaccination programs should be optimized by replacing vaccines with those adapted to local predominant PCV2d genotype,and the harm caused by PCV to pigs should be reduced through comprehensive prevention and control measures,standardized movement of live pigs and intensive monitoring of pathogens,especially during the period of high incidence.关键词
猪圆环病毒/感染调查/病原检测/病死猪Key words
PCV/investigation on infection/pathogen detection/dead pig分类
农业科技引用本文复制引用
杨治聪,侯巍,张毅,梁璐琪,李盛琼,鲁志平,王潘,刘威,邱科宇,黄海燕,黄先奇,赵文静,曹昕,刘丽,孟霞,叶鹏,阚蕊慈,冯夏妮,李春..2022-2024年四川省眉山市病死猪圆环病毒感染及猪群免疫效果调查[J].中国动物检疫,2026,43(5):15-20,6.基金项目
眉山市2021年度科技计划项目(2021YN01) （2021YN01）
四川省科技计划项目(2021ZDZX0010) （2021ZDZX0010）
2022年"天府青城计划(天府农业大师)"资助项目 （天府农业大师）
"蓉城英才计划"资助项目 （）
