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Stem cell derived neural organoid approaches for neurological diseases

Rosalie Elvira Xiao-Xue Dong Alfred Sun Xuyang Wai Hon Chooi Huck Hui Ng Hongyan Wang Yun-Cheng Wu Eng King Tan Zhi Dong Zhou

中国神经再生研究（英文版）2026，Vol.21Issue(10)：4495-4505,11.

中国神经再生研究（英文版）2026，Vol.21Issue(10)：4495-4505,11.DOI:10.4103/NRR.NRR-D-25-01004

Stem cell derived neural organoid approaches for neurological diseases

Rosalie Elvira ¹Xiao-Xue Dong ²Alfred Sun Xuyang ³Wai Hon Chooi ³Huck Hui Ng ⁴Hongyan Wang ³Yun-Cheng Wu ²Eng King Tan ⁵Zhi Dong Zhou⁶

作者信息

1. National Neuroscience Institute of Singapore,Singapore
2. Department of Neurology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,China
3. Signature Research Program in Neuroscience and Behavioral Disorders,Duke-NUS Graduate Medical School Singapore,Singapore
4. Genome Institute of Singapore,Singapore
5. National Neuroscience Institute of Singapore,Singapore||Signature Research Program in Neuroscience and Behavioral Disorders,Duke-NUS Graduate Medical School Singapore,Singapore||Department of Neurology,Singapore General Hospital,Singapore
6. National Neuroscience Institute of Singapore,Singapore||Signature Research Program in Neuroscience and Behavioral Disorders,Duke-NUS Graduate Medical School Singapore,Singapore
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摘要

关键词

neural differentiation/neural organoids/neurogenesis/neurological diseases/stem cells/three-dimensional models

Key words

neural differentiation/neural organoids/neurogenesis/neurological diseases/stem cells/three-dimensional models

引用本文复制引用

Rosalie Elvira,Xiao-Xue Dong,Alfred Sun Xuyang,Wai Hon Chooi,Huck Hui Ng,Hongyan Wang,Yun-Cheng Wu,Eng King Tan,Zhi Dong Zhou..Stem cell derived neural organoid approaches for neurological diseases[J].中国神经再生研究（英文版）,2026,21(10):4495-4505,11.

基金项目

This work was supported by the Open Fund Large Collaborative Grant(MOH-OFLCG24may-0004)and the Singapore Translational Research(STaR)Investigator Award(NMRC/STaR/0030/2018)awarded to Dr.EKT （MOH-OFLCG24may-0004）

the Open Fund-Individual Research Grant(OF-IRG,MOH-001506),Clinician Scientist-Individual Research Grants(CS-IRG)(MOH-001091,CIRG23jul-0006),HLCA2024(HLCA24Mar-0019),and SingHealth-Duke-NUS Academic Medicine Position Grant awarded to Dr.ZDZ （OF-IRG,MOH-001506）

and the National Natural Science Foundation of China(82171243)awarded to Dr.YCW. （82171243）

中国神经再生研究（英文版）

ISSN：1673-5374

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