仲恺农业工程学院学报2026，Vol.39Issue(3)：38-46,9.DOI:10.3969/j.issn.1674-5663.2026.03.006
纳米材料在肿瘤诊疗中的研究进展
Research progress of nanomaterials in tumor diagnosis and treatment
摘要
Abstract
This paper reviews the research progress of nanomaterials in tumor diagnosis and treatment using experimental data and clinical cases to inform precision oncology.Nanomaterials can be classified into three generations chronologically.The first generation uses liposomes as drug delivery carriers,reducing the toxicity of traditional therapeutics and laying the foundation for their clinical applications.The second generation expands to metal-based nanomaterials—including copper-based,iron-based,manganese-based,and gold-based systems—with gold nanoparticles pioneering new approaches in photothermal therapy.The third generation focuses on'intelligence,'enabling responsiveness to the tumor microenvironment or external stimuli to achieve precise drug release and integrated diagnosis and treatment.Despite their remarkable achievements in tumor diagnosis and treatment,nanomaterials still face challenges like tumor microenvironmental interference and suboptimal targeting efficiency.Future research should focus on multi-stimulus responsiveness and multimodal synergistic therapies to further advance precision cancer diagnosis and treatment.关键词
肿瘤治疗/脂质体/纳米材料/金属基/响应性Key words
tumor treatment/liposomes/nanomaterials/metal-based/responsiveness分类
医药卫生引用本文复制引用
关卓名,柳春玉,肖文清,李侨光..纳米材料在肿瘤诊疗中的研究进展[J].仲恺农业工程学院学报,2026,39(3):38-46,9.基金项目
广东省基础与应用基础研究基金(2025A1515011209). （2025A1515011209）
