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枸杞多糖的提取、分离纯化及药理作用

文喜艳 周鹏发 尤剑 张岩 罗燕燕 陆亚峰

中兽医医药杂志2026,Vol.45Issue(3):44-49,6.
中兽医医药杂志2026,Vol.45Issue(3):44-49,6.DOI:10.13823/j.cnki.jtcvm.2026.026

枸杞多糖的提取、分离纯化及药理作用

Extraction,isolation,purification and pharmacological effects of Lycium barbarum polysaccharides

文喜艳 1周鹏发 1尤剑 1张岩 2罗燕燕 3陆亚峰1

作者信息

  • 1. 庆阳市人民医院,甘肃 庆阳 745000
  • 2. 甘肃中医药大学附属医院,甘肃 兰州 730000
  • 3. 甘肃省中医院,甘肃 兰州 730050
  • 折叠

摘要

Abstract

Lycium barbarum is a medicinal and edible traditional Chinese medicine,with Lycium barbarum polysaccharides as its main active components.Modern research has confirmed its multiple pharmacological effects.Extraction methods for Lycium barbarum polysaccharides included hot water extraction,enzymatic hydrolysis,ultrasonic-assisted extraction,and supercritical fluid extraction technology.The extraction yield varied significantly depending on the extraction method,among which microwave-assisted composite enzyme extraction yields the highest.Separation and purification were primarily achieved through chromatography,solvent precipitation,and membrane separation techniques.The monosaccharide composition was predominantly composed of rhamnose,arabinose,and galactose,with variations in monosaccharide components across different purification processes.Lycium barbarum polysaccharides exhibit broad pharmacological effects,including antitumor activity,vision protection,antibacterial properties,hepatorenal function protection,and reproductive system support.Molecular mechanisms underlying some pharmacological effects have also been extensively studied.However,current research on Lycium barbarum polysaccharides still faces challenges such as low extraction yields,complex purification processes,and inconsistent quality standards.This review can provide references for further development and research on Lycium barbarum polysaccharides.

关键词

枸杞子/枸杞多糖/提取/分离纯化/药理作用

Key words

Lycium barbarum/Lycium barbarum polysaccharides/extraction/separation and purification/pharmacological effects

分类

农业科技

引用本文复制引用

文喜艳,周鹏发,尤剑,张岩,罗燕燕,陆亚峰..枸杞多糖的提取、分离纯化及药理作用[J].中兽医医药杂志,2026,45(3):44-49,6.

基金项目

庆阳市科技计划资助项目联合科研基金专项(QY-STK-2024A-116) (QY-STK-2024A-116)

中兽医医药杂志

1000-6354

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