郑州大学学报（医学版）2026，Vol.61Issue(3)：1-5,5.DOI:10.13705/j.issn.1671-6825.2025.11.123
食管癌和贲门癌根治术后吻合口癌的临床病理特征和意义
Clinicopathological characteristics of anastomotic carcinoma followed by radical surgery for esophageal and gastric cardia carcinoma
摘要
Abstract
Tumor recurrence or de novo primary tumors at the anastomotic site is one of the major causes of treatment failure for esophageal and gastric cardia cancer.The resection of the sphincter leads to varying degrees of gastroesophageal reflux,which may be a primary factor contributing to a series of postoperative pathological changes,and even anastomotic carcinoma at this site.However,a clear and unified definition for"anastomotic carcinoma"is currently lacking.Based on a database established by the authors,which encompasses pathological data from over 50 000 cases of esophageal and gastric cardia carcinoma post-surgery anastomoses over a 20-year period,this article elaborates on the clinicopathological character-istics of anastomotic cancer,aiming to provide a reference for the tertiary prevention of esophageal and gastric cardia cancer.关键词
食管癌/贲门癌/吻合口癌Key words
esophageal carcinoma/gastric cardia carcinoma/anastomotic carcinoma分类
医药卫生引用本文复制引用
王立东,雷豆豆,王苒,范宗民,韩雪娜,田恒运,杨海军,李秀敏,王献增,鲍启德,罗宏,纪爱芳,印明柱,高社干,张文平,宋昕,赵学科,马磊,韩文莉,雷玲玲,徐瑞华..食管癌和贲门癌根治术后吻合口癌的临床病理特征和意义[J].郑州大学学报（医学版）,2026,61(3):1-5,5.基金项目
国家科技部重大专项(2024ZD0520900,2024ZD0520906) （2024ZD0520900,2024ZD0520906）
国家自然科学基金项目(U1804262) （U1804262）
河南省科技攻关项目(232102311032) （232102311032）
