江汉大学学报（自然科学版）2026，Vol.54Issue(3)：62-71,10.DOI:10.16389/j.cnki.cn42-1737/n.2026.03.008
纳米材料介导声动力疗法治疗脑胶质瘤的研究进展
Research Progress in Nanomaterial-Mediated Sonodynamic Therapy for Glioma
摘要
Abstract
Sonodynamic therapy(SDT)induces tumor cell apoptosis through reactive oxygen species generated by sonosensitizers,providing a new therapeutic approach for glioma.However,the limited targeting ability of sonosensitizers and the presence of the blood-brain barrier(BBB)result in insufficient therapeutic efficacy of SDT.In recent years,the rapid development of nanotechnology has provided new approaches for tumor treatment.Multifunctional nanomaterials can not only overcome the shortcomings of sonosensitizers but also effectively penetrate the BBB.Therefore,SDT based on nanodelivery platforms has broad application prospects.This paper summarizes recent studies on nanomaterial-mediated SDT for glioma treatment,providing new insights and strategies for the treatment of glioma.关键词
声动力疗法/脑胶质瘤/纳米材料/治疗Key words
sonodynamic therapy/glioma/nanomaterials/treatment分类
医药卫生引用本文复制引用
张校,王皙钰,杨天天,张松,王海萍..纳米材料介导声动力疗法治疗脑胶质瘤的研究进展[J].江汉大学学报（自然科学版）,2026,54(3):62-71,10.基金项目
湖北省教育厅青年人才项目(Q20234409) （Q20234409）
