临床肝胆病杂志2026，Vol.42Issue(5)：1229-1235,7.DOI:10.12449/JCH260534
中药调控氧化应激治疗胆汁淤积性肝损伤的机制及临床应用
Mechanism and clinical application of traditional Chinese medicine in treatment of cholestatic liver injury by regulating oxidative stress
摘要
Abstract
Cholestatic liver injury(CLI)is a hepatic disorder characterized by the abnormal accumulation of bile acids in the body due to various etiologies,and without timely intervention,it can progress to liver fibrosis,liver cirrhosis,and liver failure and even lead to death.Studies have shown that modulating oxidative stress can alleviate lipid peroxidation and cellular damage,thereby suppressing inflammation and cell apoptosis.In recent years,remarkable progress has been made regarding the active components and compound prescriptions of traditional Chinese medicine in the treatment of CLI by regulating oxidative stress.This article systematically reviews the current status of research on the mechanism of action and clinical application of traditional Chinese medicine in the treatment of CLI by regulating oxidative stress.关键词
胆汁淤积/氧化性应激/中药Key words
Cholestasis/Oxidative Stress/Traditional Chinese Drugs引用本文复制引用
唐银佩,佘琳静,朱正望,王兵,朱平生..中药调控氧化应激治疗胆汁淤积性肝损伤的机制及临床应用[J].临床肝胆病杂志,2026,42(5):1229-1235,7.基金项目
国家自然科学基金(82074340) （82074340）
河南省"双一流"创建学科中医学科学研究专项(HSRP-DFCTCM-2023-1-19) （HSRP-DFCTCM-2023-1-19）
上海市"科学与创新行动计划"自然科学基金面上项目(23ZR1448400) National Natural Science Foundation of China(82074340) （23ZR1448400）
Special Project for Scientific Research of Henan Province's"Double First-Class"Creation Discipline of Traditional Chinese Medicine(HSRP-DFCTCM-2023-1-19) （HSRP-DFCTCM-2023-1-19）
Shanghai Science and Innovation Action Plan Natural Science Foundation General Project(23ZR1448400) （23ZR1448400）
