临床神经病学杂志2026，Vol.39Issue(3)：210-214,5.
良性阵发性位置性眩晕预后影响因素和残存症状的研究
Study on prognostic factors and residual symptoms of benign paroxysmal positional vertigo
摘要
Abstract
Objective To study the independent risk factors of unfavourable prognosis in the short-term of benign paroxysmal positional vertigo(BPPV),and to explore the relationship between residual symptoms and psychological factors during treatment.Methods A total of 516 consecutive patients with BPPV were retrospectively enrolled.To compare effect of short-term treatment(10 d),the patients without nystagmus and vertigo under electronystagmography were defined as the favourable-prognosis-group,other patents were enrolled in bad-prognosis-group.The clinical data were collected and compared between the two groups.Multivariate Logistic regression was used to analyze the independent risk factors of unfavourable prognosis in the short-term.To observe the medium-term(90 d)prognosis,analyze the correlation between residual symptoms and psychological factors,and the rehabilitation progress of vestibular function was evaluated by Dizziness Handicap Inventory Scale(DHI).Results There were 471 cases in the good prognosis group and 45 cases in the poor prognosis group.Univariate analysis revealed that there were statistically significant differences between the good prognosis group and the poor prognosis group in terms of anxiety,depression,age≥65 years,hospitalization status,25-hydroxyvitamin D level,cervical spondylosis,number of repositioning maneuvers<3,and duration of nystagmus(all P<0.05).Multivariate Logistic regression analysis showed that cervical spondylosis(OR=6.498,95%CI:1.755-24.063,P=0.005),outpatient(OR=1.397,95%CI:1.075-1.816,P=0.012),nystagmus lasts more than 60 s each time(OR=2.625,95%CI:1.848-3.730,P<0.01),and number of manual reduction(OR=1.216,95%CI:1.081-1.367,P=0.001)were independent risk factors affecting the short-term recovery of BPPV.After 90 d of treatment,there was a significant difference in the scores of emotional index in DHI between the two groups(P<0.05),but there was no significant difference in the scores of somatic index and functional index.Conclusions The prognosis of BPPV is good.Cervical spondylosis,outpatient treatment,duration of nystagmus and times of reduction are independent risk factors affecting the short-term recovery of BPPV.Residual symptoms was positively correlated with anxiety and depression scores.关键词
良性阵发性位置性眩晕/短期预后/中期预后/手法复位/半规管Key words
benign paroxysmal positional vertigo/short-term prognosis/medium-term prognosis/manual reduction/semicircular canal分类
医药卫生引用本文复制引用
田鸿福,王宇,顾嘉晨,艾志兵,邱峰..良性阵发性位置性眩晕预后影响因素和残存症状的研究[J].临床神经病学杂志,2026,39(3):210-214,5.基金项目
南京市卫生科技发展专项资金项目计划(ZKX23039) （ZKX23039）
