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面向免疫固定电泳分类的输入增强双尺度网络模型

符笑添 谢剑宇 谭子涵 李曙

吉首大学学报(自然科学版)2026,Vol.47Issue(3):41-49,9.
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吉首大学学报(自然科学版)2026,Vol.47Issue(3):41-49,9.DOI:10.13438/j.cnki.jdzk.2026.03.007

面向免疫固定电泳分类的输入增强双尺度网络模型

Input-Enhanced Dual-Scale Network for Immunofixation Electrophoresis Image Classification

符笑添 1谢剑宇 1谭子涵 1李曙2

作者信息

  • 1. 吉首大学通信与电子工程学院,湖南 吉首 416000
  • 2. 广州医科大学生物医学工程学院,广东 广州 511000
  • 折叠

摘要

Abstract

To address the clinical challenges of immunofixation electrophoresis images,such as background fluctuations,noise interference,and faint bands leading to missed detections and misdiagnoses,we pro-pose a DGDB-IE2FNet model.The model features a dynamically gated dual-branch residual block and an IFE input enhancement dual-scale branch.The former adaptively fuses complementary convolutional branches,while the latter suppresses background noise and enhances directional information of bands.We formulate the classification of positive/negative results for ELP,G,A,M,K,and L lanes as a multi-label prediction task and conduct comparative experiments with several mainstream models using 20 000 real-world cases.Results show that the DGDB-IE2FNet achieves an accuracy of 99.63%,negative predictive value of 99.74%,sensitivity of 98.07%,and F1 score of 98.56%on the test set,outperforming other compared models in overall prediction performance.

关键词

免疫固定电泳/深度学习/卷积神经网络/双尺度

Key words

immunofixation electrophoresis/deep learning/convolutional neural networks/dual-scale

分类

信息技术与安全科学

引用本文复制引用

符笑添,谢剑宇,谭子涵,李曙..面向免疫固定电泳分类的输入增强双尺度网络模型[J].吉首大学学报(自然科学版),2026,47(3):41-49,9.

吉首大学学报(自然科学版)

1007-2985

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