实用中医内科杂志2026，Vol.40Issue(6)：77-80,4.DOI:10.13729/j.issn.1671-7813.Z25082707
基于"虚气留滞"理论探讨脾瘅方运用扶正祛邪法治疗糖尿病前期
Exploration on Application of Pidan Prescription(脾瘅方)in Treating Prediabetes by Method of Sup-porting Healthy Qi and Eliminating Pathogenic Factors Based on Theory of"Stagnation of Deficient Qi"
摘要
Abstract
Prediabetes,a critical transitional stage to type 2 diabetes,aligns closely with the traditional Chinese medi-cine(TCM)theory of"Stagnation of deficient Qi".This study systematically explored the theoretical and clinical applica-tion of Pidan Prescription(脾瘅方)in treating prediabetes through the TCM approach of"supporting healthy qi and elimi-nating pathogenic factors".Rooted in classical texts such as Suwen and Treatise on the Spleen and Stomach,the pathogene-sis of Pidan Prescription is attributed to spleen deficiency leading to stagnation of Qi,blood and body fluids,resulting in phlegm-dampness,blood stasis and heat accumulation.Pidan Prescription employs bran-fried Cangzhu(Atractylodis Rhi-zoma)and Baizhu(Atractylodis Macrocephalae Rhizoma)as monarch herbs to strengthen spleen and resolve dampness,com-plemented by Huanglian(Coptidis Rhizoma)and Zhizi(Gardeniae Fructus)to clear heat,Gualou(Trichosanthis Fructus)and Zhishi(Aurantii Fructus Immaturus)to dispel phlegm-stagnation,and Guijianyu(Ramulus Euonymi)to activate blood circu-lation.This formula embodies the TCM principle of"restoring Qi transformation and resolving stagnation"through harmo-nizing the liver-spleen axis,regulating Qi movement and eliminating pathological products.Modern research confirms its multi-target effects,including improving insulin resistance via MAPK/AMPK pathways and modulating gut microbiota,while alleviating fatigue and obesity.Compared to Western medicine single-target approach,Pidan Formula integrates nat-ural components with holistic regulation,offering a safer and more comprehensive TCM strategy for prediabetes manage-ment.关键词
糖尿病前期/虚气留滞/脾瘅方/扶正祛邪法Key words
prediabetes/deficient Qi Stagnation/Pidan Formula(脾瘅方)/method of supporting healthy Qi and elimi-nating pathogenic factors分类
医药卫生引用本文复制引用
石雨奇,李继安,胡宝丰,张云芬..基于"虚气留滞"理论探讨脾瘅方运用扶正祛邪法治疗糖尿病前期[J].实用中医内科杂志,2026,40(6):77-80,4.基金项目
河北省自然科学基金资助项目(中医药联合基金重点项目)(H2023209038) （中医药联合基金重点项目）
