特产研究2026，Vol.48Issue(3)：37-44,56,9.DOI:10.16720/j.cnki.tcyj.2025.024
基于AHP-CRITIC结合Box-Behnken响应面法优选壮药复方葛花颗粒的提取工艺
Optimization of the Extraction Process of Zhuang Medicine Compound Gehua Granules based on AHP-CRITIC Combined with Box-Behnken Re-sponse Surface Methodology
张宇鹏 1张儒伟 1唐攀 1陈思霞 1田森明 1梁丹 1冷静2
作者信息
- 1. 广西中医药大学药学院,广西 南宁 530200||广西高校中药制剂共性技术研发重点实验室,广西 南宁 530200
- 2. 广西高发传染病中西医结合转化医学重点实验室,广西 南宁 530200
- 折叠
摘要
Abstract
To optimize the extraction process of Zhuang Medicine Compound Gehua granules based on AHP-CRITIC combined with Box-Behnken response surface methodology.The content of tectoridin,dihydromyricetin and extraction yield in Zhuang Medicine Compound Gehua granules were used as the evaluation indicators.The comprehensive weight coefficients of each indicator were calculated using Analytic Hierarchy Process(AHP)combined with CRITIC method.Taking the water addition ratio,extraction time,and extraction frequency as the examination factors,a multi index comprehensive score combined with Box-Behnken response surface method was used to design experiments and optimize the water extraction process of Zhuang Medicine Compound gehua Granules.The optimal process for the Zhuang Medicine Compound Gehua granules was to selected as adding 12 times of water volume,with extraction time for 1.5 h,and 3 extractions.The extraction process of the Zhuang Medicine Compound Gehua granules determined in this study is stable and feasible,which can provide a reference for the industrial production of Zhuang Medicine Compound Gehua Granules.关键词
AHP-CRITIC/Box-Behnken响应面法/壮药复方葛花颗粒/鸢尾苷/二氢杨梅素Key words
AHP-CRITIC/Box-Behnken response surface methodology/Zhuang Medicine Compound Gehua granules/tectoridin/di-hydromyricetin分类
医药卫生引用本文复制引用
张宇鹏,张儒伟,唐攀,陈思霞,田森明,梁丹,冷静..基于AHP-CRITIC结合Box-Behnken响应面法优选壮药复方葛花颗粒的提取工艺[J].特产研究,2026,48(3):37-44,56,9.
