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静电纺聚乳酸-羟基乙酸基纳米纤维在生物医药领域的研究进展

裘鑫涛 徐梓豪 王家豪 白育庭 闵清 要辉

湖北科技学院学报(医学版)2026,Vol.40Issue(3):266-270,5.
湖北科技学院学报(医学版)2026,Vol.40Issue(3):266-270,5.DOI:10.16751/j.cnki.2095-4646.2026011705

静电纺聚乳酸-羟基乙酸基纳米纤维在生物医药领域的研究进展

Research Progress on Electrospun Poly(lactic-co-glycolic acid)-Based Nanofibers in the Biomedical Field

裘鑫涛 1徐梓豪 1王家豪 1白育庭 2闵清 3要辉3

作者信息

  • 1. 湖北科技学院医学部药学院,湖北 咸宁 437100
  • 2. 湖北科技学院医学部临床医学院
  • 3. 湖北科技学院医学部药学院,湖北 咸宁 437100||鄂南特色中药湖北省工程研究中心
  • 折叠

摘要

Abstract

Poly(lactic-co-glycolic acid)(PLGA)has garnered widespread attention in the biomedical field due to its good biocom-patibility and tunable degradation properties.Electrospinning technology can prepare nanofibers with high specific surface area and biomimet-ic extracellular matrix structure,providing an ideal technical route for the molding and processing of PLGA,as well as expanding its potential applications.This article outlines the fundamentals of PLGA material and the principles of electrospinning,summarizes strategies for the functional modification of PLGA,and focuses on reviewing its latest research achievements in the biomedical fields of drug delivery,tissue engineering,and wound dressings,clarifying the application value of such materials in precision medicine and regenerative medicine,and providing targeted references for the technical optimization and clinical translation of related research.

关键词

PLGA/静电纺丝/纳米纤维/药物递送/组织工程/伤口敷料

Key words

PLGA/Electrospinning/Nanofibers/Drug delivery/Tissue engineering/Wound dressings

分类

医药卫生

引用本文复制引用

裘鑫涛,徐梓豪,王家豪,白育庭,闵清,要辉..静电纺聚乳酸-羟基乙酸基纳米纤维在生物医药领域的研究进展[J].湖北科技学院学报(医学版),2026,40(3):266-270,5.

基金项目

湖北省中医药联合基金项目(ZY2025L022) (ZY2025L022)

湖北科技学院博士启动项目(BK202206) (BK202206)

湖北科技学院学报(医学版)

2095-4646

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