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亚精胺在卵巢早衰患者中的作用及其研究进展

张一凡 张国忠 自永宏

医学信息2026,Vol.39Issue(11):179-182,4.
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医学信息2026,Vol.39Issue(11):179-182,4.DOI:10.3969/j.issn.1006-1959.2026.11.036

亚精胺在卵巢早衰患者中的作用及其研究进展

Role of Spermidine in Patients with Premature Ovarian Failure and its Research Progress

张一凡 1张国忠 1自永宏1

作者信息

  • 1. 攀枝花市妇幼保健院生殖医学中心/攀枝花市生殖医学重点实验室,四川 攀枝花 617000
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摘要

Abstract

Premature ovarian Failure(POF)is a disease that seriously affects female fertility,with complex and diverse etiologies,bringing tremendous psychological and physiological burdens to patients.In recent years,spermidine,as an important polyamine compound,has received widespread attention due to its potential roles in cell proliferation,apoptosis,and reproductive health.It may have a positive impact on POF patients by regulating ovarian function,improving cell oxidative stress level and promoting oocyte quality.This provides new ideas and directions for the research and clinical application of spermidine in POF.This review discusses the relationship between spermidine and POF,and analyzes its role in the pathogenesis of POF and its prospects as a potential treatment strategy in the future.

关键词

亚精胺/卵巢早衰/生殖健康/细胞增殖/氧化应激/卵母细胞

Key words

Spermidine/Premature ovarian failure/Reproductive health/Cell proliferation/Oxidative stress/Oocytes

分类

医药卫生

引用本文复制引用

张一凡,张国忠,自永宏..亚精胺在卵巢早衰患者中的作用及其研究进展[J].医学信息,2026,39(11):179-182,4.

基金项目

攀枝花市指导性科技计划项目(编号:2023ZD-S-32) (编号:2023ZD-S-32)

医学信息

1006-1959

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