针刺研究2026，Vol.51Issue(6)：803-808,6.DOI:10.13702/j.1000-0607.20250664
离体心脏灌流与钙瞬变心肌收缩测量联合技术在针灸心血管保护机制研究中的应用前景
Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture
摘要
Abstract
Acupuncture has demonstrated unique potential in the treatment of cardiovascular diseases,yet its further scientific advancement and international recognition still require breakthroughs in mechanism research and evidence strengthening.Isolated heart perfusion technique and calcium transient myocardial contraction measurement technique have provided new perspectives and methods for cardiac research.However,due to experimental limitations,these two techniques have rarely been utilized in acupuncture research.Integrating and applying these two technologies in acupuncture research can enable precise quantification of the multi-target regulatory effects of acupuncture on the autonomic nervous system-calcium cycle at the cellular level,as well as accurate evaluation of the synergistic and/or antagonistic interactions between acupuncture and medication in treating cardiovascular diseases.This integration will provide an effective means to deeply elucidate the calcium-regulation mechanisms underlying the cardiovascular effects of acupuncture.Through detailed analysis of the principles,applications,and advantages of these two technologies,this article further explores their application prospects in the research of cardiovascular modulation mechanism of acupuncture,thereby expanding new fields and directions in basic research of acupuncture.关键词
针灸/离体心脏/钙瞬变/收缩功能/心血管疾病Key words
Acupuncture/Isolated heart/Calcium transients/Contractile function/Cardiovascular disease引用本文复制引用
辛娟娟,刘群,江天云,赵玉雪,闫文茜,喻晓春,高俊虹..离体心脏灌流与钙瞬变心肌收缩测量联合技术在针灸心血管保护机制研究中的应用前景[J].针刺研究,2026,51(6):803-808,6.基金项目
国家自然科学基金项目(No.82174520、81804211) （No.82174520、81804211）
中央级公益性科研院所基本科研业务费专项资金资助项目(No.ZZ-2023007) （No.ZZ-2023007）
