中国医学创新2026，Vol.23Issue(15)：104-108,5.DOI:10.3969/j.issn.1674-4985.2026.15.022
体感诱发电位N20对重型颅脑损伤患者短期预后的预测价值
Predictive Value of Somatosensory Evoked Potential N20 for Short-term Prognosis of Patients with Severe Craniocerebral Injury
摘要
Abstract
Objective:To explore the predictive value of somatosensory evoked potential N20 for the short-term prognosis of patients with severe craniocerebral injury.Method:A total of 103 patients with severe craniocerebral injury admitted to Jincheng People's Hospital from June 2023 to June 2025 were selected.Somatosensory evoked potential N20 monitoring was conducted on the 3rd day after admission,and the clinical data of the patients were collected.After 3 months of follow-up,the patients were divided into the good prognosis group(n=70)and the poor prognosis group(n=33)according to the Glasgow outcome scale(GOS)score.The clinical data,N20 latent phase and N20 amplitude of the two groups were compared.Multivariate logistic regression analysis was used to analyze the influencing factors affecting the short-term prognosis of patients with severe craniocerebral injury.The ROC curve was plotted to analyze the predictive value of N20 latent phase and N20 amplitude for the prognosis of patients.Result:The acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)score of the poor prognosis group was higher than that of the good prognosis group(P<0.05).There were no statistically significant differences in gender,age,body mass index,underlying diseases,causes of injury,time from injury to admission,and GCS score between the two groups(P>0.05).The N20 latent phase in the poor prognosis group was longer than that in the good prognosis group,and the N20 amplitude was shorter than that in the good prognosis group(P<0.05).Multivariate logistic regression analysis showed that N20 latent phase and N20 amplitude were influencing factors for the short-term poor prognosis of patients with severe craniocerebral injury(P<0.05).The AUC of combined detection of N20 latent phase and N20 amplitude in predicting the short-term prognosis of patients with severe craniocerebral injury was 0.922,which was higher than that of individual detection of each parameter(P<0.05).Conclusion:There is a certain relationship between the monitoring of N20 latent phase and N20 amplitude by somatosensory evoked potential and the short-term prognosis of patients with severe craniocerebral injury,and the combined application can improve the predictive value of the short-term prognosis of patients.关键词
重型颅脑损伤/体感诱发电位/N20波幅/短期预后/预测价值Key words
Severe craniocerebral injury/Somatosensory evoked potential/N20 amplitude/Short-term prognosis/Predictive value分类
医药卫生引用本文复制引用
申剑波,乔凯鹏..体感诱发电位N20对重型颅脑损伤患者短期预后的预测价值[J].中国医学创新,2026,23(15):104-108,5.基金项目
山西省"四个一批"科技兴医创新计划项目(2022XM24) （2022XM24）
晋城市科技局项目(20210104) （20210104）
