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增强型体外反搏对心力衰竭合并认知障碍患者的疗效研究

刘加齐 李方江 秦少强 张爱爱 王子帅

神经药理学报2026,Vol.16Issue(2):29-35,7.
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神经药理学报2026,Vol.16Issue(2):29-35,7.DOI:10.3969/j.issn.2095-1396.2026.02.004

增强型体外反搏对心力衰竭合并认知障碍患者的疗效研究

Effect of Enhanced External Counterpulsation on Quality of Life,Cardiac Function,and Cognitive Function in Patients with Heart Failure and Cognitive Impairment

刘加齐 1李方江 2秦少强 2张爱爱 2王子帅1

作者信息

  • 1. 河北北方学院研究生学院,张家口,075000,中国
  • 2. 河北北方学院附属第一医院心血管内科,张家口,075000,中国
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摘要

Abstract

Objective:To observe the effects of enhanced external counterpulsation(EECP)on quality of life,cardiac function,and cognitive function in patients with heart failure complicated cognitive impairment.Methods:Ninety patients were randomly assigned to either a control group or an observation group,with 45 patients in each.The control group received standard heart failure treatment,while the observation group received EECP in addition to the standard treatment.After 7 weeks of treatment,comparisons were made between the two groups regarding the Minnesota living with heart failure questionnaire(MLHFQ)score,left ventricular ejection fraction(LVEF),6-minute walking distance(6MWD),ratio of early to late diastolic ventricular filling velocities(E/A ratio),New York Heart Association(NYHA)functional classification,left ventricular end-diastolic dimension(LVEDD),N-terminal pro-B-type natriuretic peptide(NT-proBNP)levels,high-sensitivity C-reactive protein(hs-CRP)levels,30-day readmission rate,activities of daily living(ADL)scale score,and Montreal cognitive assessment(MoCA)score.Results:After treatment,the MLHFQ scores decreased in both groups,with a more significant decrease observed in the EECP group(P<0.05).Regarding cardiac function,the EECP group showed superior improvement in LVEF,6MWD,E/A ratio,and NYHA classification,as well as a greater reduction in LVEDD,NT-proBNP,and hs-CRP levels compared to the control group(P<0.05).However,no statistically significant difference was found in the 30-day readmission rate between the two groups(P>0.05).Regarding cognitive function,the MoCA scores increased and ADL scores improved more significantly in the EECP group compared to the control group(P<0.05);the control group showed no significant change in MoCA scores.Conclusion:EECP is beneficial for improving quality of life,cardiac function,and cognitive function in patients with heart failure complicated by cognitive impairment.

关键词

增强型体外反搏/心力衰竭/认知障碍/疗效评估

Key words

enhanced external counterpulsation/heart failure/cognitive impairment/therapeutic evaluation

分类

医药卫生

引用本文复制引用

刘加齐,李方江,秦少强,张爱爱,王子帅..增强型体外反搏对心力衰竭合并认知障碍患者的疗效研究[J].神经药理学报,2026,16(2):29-35,7.

神经药理学报

2095-1396

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