摘要
Abstract
Objective:To observe the effects of enhanced external counterpulsation(EECP)on quality of life,cardiac function,and cognitive function in patients with heart failure complicated cognitive impairment.Methods:Ninety patients were randomly assigned to either a control group or an observation group,with 45 patients in each.The control group received standard heart failure treatment,while the observation group received EECP in addition to the standard treatment.After 7 weeks of treatment,comparisons were made between the two groups regarding the Minnesota living with heart failure questionnaire(MLHFQ)score,left ventricular ejection fraction(LVEF),6-minute walking distance(6MWD),ratio of early to late diastolic ventricular filling velocities(E/A ratio),New York Heart Association(NYHA)functional classification,left ventricular end-diastolic dimension(LVEDD),N-terminal pro-B-type natriuretic peptide(NT-proBNP)levels,high-sensitivity C-reactive protein(hs-CRP)levels,30-day readmission rate,activities of daily living(ADL)scale score,and Montreal cognitive assessment(MoCA)score.Results:After treatment,the MLHFQ scores decreased in both groups,with a more significant decrease observed in the EECP group(P<0.05).Regarding cardiac function,the EECP group showed superior improvement in LVEF,6MWD,E/A ratio,and NYHA classification,as well as a greater reduction in LVEDD,NT-proBNP,and hs-CRP levels compared to the control group(P<0.05).However,no statistically significant difference was found in the 30-day readmission rate between the two groups(P>0.05).Regarding cognitive function,the MoCA scores increased and ADL scores improved more significantly in the EECP group compared to the control group(P<0.05);the control group showed no significant change in MoCA scores.Conclusion:EECP is beneficial for improving quality of life,cardiac function,and cognitive function in patients with heart failure complicated by cognitive impairment.关键词
增强型体外反搏/心力衰竭/认知障碍/疗效评估Key words
enhanced external counterpulsation/heart failure/cognitive impairment/therapeutic evaluation分类
医药卫生