中国合理用药探索2026,Vol.23Issue(5):119-126,8.DOI:10.3969/j.issn.2096-3327.2026.05.017
芪龙活络方联合温阳针灸法治疗气虚血瘀型脑梗死恢复期患者的效果观察
Efficacy Observation on Qilong Huoluo Formula Combined with Wenyang Acupuncture in Treating Cerebral Infarction Patients at Recovery Stage with Qi Deficiency and Blood Stasis Syndrome
摘要
Abstract
Objective:To explore the clinical effect of Qilong Huoluo Formula combined with Wenyang Acupuncture in the treatment of cerebral infarction patients at recovery stage with qi deficiency and blood stasis syndrome.Methods:A total of 80 cerebral infarction patients at recovery stage with qi deficiency and blood stasis syndrome admitted from March to October 2025 were selected and divided into control group and observation group by random number table method,with 40 cases in each group.The control group received conventional treatment;the observation group was treated with Qilong Huoluo Formula combined with Wenyang Acupuncture on the basis of the control group,with continuous treatment for 4 weeks.Clinical efficacy,traditional Chinese medicine(TCM)syndrome score,motor function(evaluated by the Fugl-Meyer Assessment Scale),quality of life[evaluated by the Stroke-Specific Quality of Life(SS-QOL)],hemorheological indexes(plasma viscosity,whole blood high shear viscosity,whole blood low shear viscosity),neuro-related indicators[5-hydroxytryptamine(5-HT),brain-derived neurotrophic factor(BDNF),neuron-specific enolase(NSE)]and adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 92.50%,higher than 70.00%of the control group(P<0.05).TCM syndrome score,plasma viscosity,whole blood high shear viscosity,whole blood low shear viscosity and serum NSE in the observation group were lower than those of the control group;Fugl-Meyer score(upper limb and lower limb),SS-QOL score,serum 5-HT and BDNF were higher than those of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Qilong Huoluo Formula combined with Wenyang Acupuncture can improve clinical efficacy,reduce blood viscosity,regulate neuro-related indicators levels,and improve motor function and quality of life in cerebral infarction patients at recovery stage with qi deficiency and blood stasis syndrome.关键词
脑梗死/恢复期/气虚血瘀型/芪龙活络方/温阳针灸法Key words
cerebral infarction/recovery stage/qi deficiency and blood stasis syndrome/Qilong Huoluo Formula/Wenyang Acupuncture分类
医药卫生引用本文复制引用
赵敏,范晓飞,段云飞,张新慧,韩文刚,唐然..芪龙活络方联合温阳针灸法治疗气虚血瘀型脑梗死恢复期患者的效果观察[J].中国合理用药探索,2026,23(5):119-126,8.基金项目
河南省中医药科学研究专项课题(2022ZY1026) (2022ZY1026)