中医药信息2026，Vol.43Issue(6)：91-98,8.DOI:10.19656/j.cnki.1002-2406.20260614
小肠细菌过度生长伴肠易激综合征的病理机制与中医药治疗研究进展
Research Progress on the Pathological Mechanisms and Traditional Chinese Medicine Treatment of Small Intestinal Bacterial Overgrowth with Irritable Bowel Syndrome
摘要
Abstract
Irritable bowel syndrome(IBS)is a common functional bowel disorder clinically,which is characterized by a complex etiology involving the interplay of multiple factors.Small intestinal bacterial overgrowth(SIBO)plays a critical role in the pathogenesis of IBS.The significant overlap in clinical symptoms of IBS and SIBO suggests that SIBO may contribute to the onset and progression of IBS via multiple pathways,including impaired intestinal motility,damage to the intestinal mucosal barrier,activation of immune-inflammatory responses,and disruption of the Gut-Brain Axis.By systematically reviewing the association between IBS and SIBO,their underlying mechanisms,and the therapeutic advances in traditional Chinese medicine(TCM),it is found that TCM,capitalizing on its multi-target and holistic regulatory approach,exhibits unique potential in inhibiting bacterial overgrowth,alleviating inflammation,and modulating gastrointestinal motility,and is associated with a low recurrence rate.关键词
小肠细菌过度生长/肠易激综合征/中医药Key words
Small intestinal bacterial overgrowth/Irritable bowel syndrome/Traditional Chinese medicine引用本文复制引用
张玥,唐莉,杨勤..小肠细菌过度生长伴肠易激综合征的病理机制与中医药治疗研究进展[J].中医药信息,2026,43(6):91-98,8.基金项目
江苏省中医药科技发展计划项目(MS2023055) （MS2023055）
南京卫生科技发展专项重点项目(ZKX21058) （ZKX21058）
南京市中医药传承创新发展示范试点资助项目(NJCC-ZJ-202416) （NJCC-ZJ-202416）
南京市中医院院内制剂研究备案项目(ZJ2022011) （ZJ2022011）
