安全、健康和环境2026，Vol.26Issue(6)：1-14,14.DOI:10.3969/j.issn.1672-7932.2026.06.001
过程强化技术在化工过程本质安全化中的应用进展
Advances in the Application of Process Intensification Technologies for Inherent Safer Chemical Processes
摘要
Abstract
Process intensification through technologies such as equipment miniaturization and external field enhancement improves reaction efficiency while regulating the inventory of hazardous materials and operating conditions.This closely aligns with inherent safety design principles and has become a crucial approach to a-chieving inherent safety in chemical processes,making the integration of process intensification and inherent safety concepts a vital research direction in chemical safety.Accordingly,this study explored typical process in-tensification technologies,including microreactors,membrane reactors,and high-gravity technology.Specifical-ly,microreactors,characterized by high specific surface areas and low liquid hold-up,can reduce hazardous material inventories to the microliter scale,significantly improving reaction conversion while minimizing hazard-ous material usage.Membrane reactors achieve the real-time separation of hazardous byproducts through the coupling of reaction and separation,offering both safety and environmental benefits.Additionally,high-gravity technology intensifies mass transfer and mixing,shortens reaction times,and enables milder operating condi-tions,thereby effectively reducing the risk of runaway reactions.Regarding frontier research directions,biomim-etic technology can guide the development of novel,safe,and efficient equipment;artificial intelligence-driven systems can monitor risks in real time,intelligently control operations,and enhance intensification effects;and quantum computing facilitates more accurate reaction simulations and risk predictions,providing robust support for process safety design.Future research should focus on developing synergistic optimization methods for safety and efficiency tailored to complex process intensification systems.Furthermore,deepening the integration of safety databases,mechanistic models,and intelligent algorithms will significantly elevate the application of process intensification technologies in empowering inherently safer chemical processes.关键词
化工过程/本质安全化/过程强化/反应器优化/仿生技术/人工智能/量子计算Key words
chemical process/inherent safety/process intensification/reactor optimization/biomimetic technology/artificial intelligence/quantum computing分类
资源环境引用本文复制引用
冯俊杰..过程强化技术在化工过程本质安全化中的应用进展[J].安全、健康和环境,2026,26(6):1-14,14.基金项目
国家自然科学基金(21908249),多相微反应器内限域结构影响下的气泡形变与破裂机理研究. （21908249）
