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Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Yaqiang Hu Zhiyang Zeng Xinyu Ming Shuming Yin Yuting Guan Liangcai Gao Dali Li

动物模型与实验医学（英文）2026，Vol.9Issue(3)：537-545,9.

动物模型与实验医学（英文）2026，Vol.9Issue(3)：537-545,9.DOI:10.1002/ame2.70082

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Yaqiang Hu ¹Zhiyang Zeng ²Xinyu Ming ¹Shuming Yin ¹Yuting Guan ¹Liangcai Gao ¹Dali Li¹

作者信息

1. Shanghai Frontiers Science Center of Genome Editing and Cell Therapy,Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai,China
2. Fengxian Central Hospital Affiliated to Southern Medical University,Shanghai,China
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摘要

关键词

CRISPR/Cas9/endoplasmic reticulum stress/mouse model/neurodegenerative diseases/Sec16a

Key words

CRISPR/Cas9/endoplasmic reticulum stress/mouse model/neurodegenerative diseases/Sec16a

引用本文复制引用

Yaqiang Hu,Zhiyang Zeng,Xinyu Ming,Shuming Yin,Yuting Guan,Liangcai Gao,Dali Li..Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9[J].动物模型与实验医学（英文）,2026,9(3):537-545,9.

基金项目

The Chunhui Program of the ministry of Education,Grant/Award Number:HZKY20220076 （）

the Shanghai Municipal Commission of Science and Technology,Grant/Award Number:21JC1402200,22YF1437700 and 23HC1400700 （）

National Natural Science Foundation of China,Grant/Award Number:32200732 （）

National Key Research and Development Program of China,Grant/Award Number:2022YFC3400200 （）

动物模型与实验医学（英文）

ISSN：2096-5451

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