感染、炎症、修复2026，Vol.27Issue(3)：267-271,5.DOI:10.3969/j.issn.1672-8521.2026.03.009
脓毒症后综合征的病理生理学机制研究进展
Research progress on the pathophysiological mechanisms of post-sepsis syndrome
摘要
Abstract
Post-sepsis syndrome(PSS)is a clinical syndrome that occurs after sepsis and is difficult to explain with other diseases.It is characterized by long-term physical,cognitive,and psychosocial problems that significantly affect the long-term quality of life of sepsis survivors.The pathophysiological evolution does not merely extend from acute organ damage but involves a continuous process of acute metabolic-immune reprogramming,persistent inflammation-immunosuppression-catabolism syndrome(PICS),leading to chronic organ remodeling.This review aims to provide a theoretical basis for stratified intervention strategies for post-sepsis syndrome from the above perspectives.关键词
脓毒症/脓毒症后综合征/代谢重编程/持续性炎症-免疫抑制-分解代谢综合征/靶器官损伤Key words
sepsis/post-sepsis syndrome/metabolic reprogramming/persistent inflammation-immunosuppression-catabolism syndrome/target organ injury引用本文复制引用
姚奕,赵光举..脓毒症后综合征的病理生理学机制研究进展[J].感染、炎症、修复,2026,27(3):267-271,5.基金项目
国家自然科学基金(82272202),温州市高水平创新团队项目(2024R3002). （82272202）
