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惊恐障碍脑电图研究进展:现状、挑战与展望

吴思燕 张函 史珂 夏叶 王紫薇 冯捷 杨渊

神经损伤与功能重建2026,Vol.21Issue(6):354-357,369,5.
神经损伤与功能重建2026,Vol.21Issue(6):354-357,369,5.DOI:10.16780/j.cnki.sjssgncj.20251052

惊恐障碍脑电图研究进展:现状、挑战与展望

Research Progress on EEG in Panic Disorder:Current Status,Challenges,and Future Prospects

吴思燕 1张函 1史珂 1夏叶 1王紫薇 1冯捷 1杨渊1

作者信息

  • 1. 华中科技大学同济医学院附属同济医院神经内科 武汉 430000
  • 折叠

摘要

Abstract

Panic disorder is a common acute anxiety disorder characterized by sudden panic attacks that severely impact patients' daily lives.In recent years,electroencephalogram(EEG)and event-related potentials(ERP)techniques have played a crucial role in elucidating the neural mechanisms underlying this condition.Resting-state EEG studies have demonstrated abnormalities such as frontal alpha asymmetry,altered EEG microstates and impaired functional brain network connectivity in patients with panic disorder.Meanwhile,ERP investigations using paradigms such as Oddball,Go/NoGo,Stroop and Flanker have revealed deficits in cognitive functions including attentional allocation,inhibitory control and error monitoring.However,existing research is limited by methodological heterogeneity,small sample sizes and a lack of longitudinal designs.Future studies should focus on establishing standardized protocols,promoting multi-center collaborations with larger samples and incorporating advanced techniques such as high-density EEG,source localization,machine learning and longitudinal studies.This integrated approach is critical to identifying reliable neuroelectrophysiological biomarkers for the early diagnosis and personalized treatment of panic disorder.

关键词

惊恐障碍/脑电图/事件相关电位

Key words

panic disorder/electroencephalography/event-related potentials

分类

医药卫生

引用本文复制引用

吴思燕,张函,史珂,夏叶,王紫薇,冯捷,杨渊..惊恐障碍脑电图研究进展:现状、挑战与展望[J].神经损伤与功能重建,2026,21(6):354-357,369,5.

基金项目

国家自然科学基金项目(疫情相关焦虑障碍风险预测模型建立及多模态诊疗新方案的研究,No.82090034) (疫情相关焦虑障碍风险预测模型建立及多模态诊疗新方案的研究,No.82090034)

神经损伤与功能重建

1001-117X

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