神经损伤与功能重建2026,Vol.21Issue(6):354-357,369,5.DOI:10.16780/j.cnki.sjssgncj.20251052
惊恐障碍脑电图研究进展:现状、挑战与展望
Research Progress on EEG in Panic Disorder:Current Status,Challenges,and Future Prospects
摘要
Abstract
Panic disorder is a common acute anxiety disorder characterized by sudden panic attacks that severely impact patients' daily lives.In recent years,electroencephalogram(EEG)and event-related potentials(ERP)techniques have played a crucial role in elucidating the neural mechanisms underlying this condition.Resting-state EEG studies have demonstrated abnormalities such as frontal alpha asymmetry,altered EEG microstates and impaired functional brain network connectivity in patients with panic disorder.Meanwhile,ERP investigations using paradigms such as Oddball,Go/NoGo,Stroop and Flanker have revealed deficits in cognitive functions including attentional allocation,inhibitory control and error monitoring.However,existing research is limited by methodological heterogeneity,small sample sizes and a lack of longitudinal designs.Future studies should focus on establishing standardized protocols,promoting multi-center collaborations with larger samples and incorporating advanced techniques such as high-density EEG,source localization,machine learning and longitudinal studies.This integrated approach is critical to identifying reliable neuroelectrophysiological biomarkers for the early diagnosis and personalized treatment of panic disorder.关键词
惊恐障碍/脑电图/事件相关电位Key words
panic disorder/electroencephalography/event-related potentials分类
医药卫生引用本文复制引用
吴思燕,张函,史珂,夏叶,王紫薇,冯捷,杨渊..惊恐障碍脑电图研究进展:现状、挑战与展望[J].神经损伤与功能重建,2026,21(6):354-357,369,5.基金项目
国家自然科学基金项目(疫情相关焦虑障碍风险预测模型建立及多模态诊疗新方案的研究,No.82090034) (疫情相关焦虑障碍风险预测模型建立及多模态诊疗新方案的研究,No.82090034)