湖南中医药大学学报2026，Vol.46Issue(6)：1297-1302,6.DOI:10.3969/j.issn.1674-070X.2026.06.030
《伤寒论》三阴辨证视角下多囊卵巢综合征高雄激素血症病机与方药研究进展
Research progress on pathogenesis and formulas for hyperandrogenism in polycystic ovary syndrome from the perspective of three-yin pattern differentiation in Shang Han Lun(Treatise on Cold Damage)
摘要
Abstract
Polycystic ovary syndrome(PCOS)-associated hyperandrogenism is a complex female endocrine and metabolic disorder.Current modern medical treatments primarily focus on anti-androgen therapies and metabolic regulation.Based on the three-yin pattern differentiation theory from the Shang Han Lun(Treatise on Cold Damage),this paper systematically reviews the TCM pathogenesis evolution and classical formula treatment rules of this disease.It proposes that the pathological essence of this disease lies in the interwoven network of deficiency and cold across the three yin zang organs:Taiyin spleen deficiency with dampness exuberance,which closely corresponds to glycolipid metabolism disorders and insulin resistance;Shaoyin kidney essence deficiency,which serves as the root of hypothalamic-pituitary-ovarian(HPO)axis dysregulation;and Jueyin cold-heat complexity,which reflects the network cascade of neuroendocrine and immune stress responses.Based on this multidimensional pathogenesis,this paper reviews the targeted intervention mechanisms of classical formulas such as Lizhong Pill,Shenqi Pill,and Wumei Pill,aiming to transcend the limitations of single-target therapy and provide new clinical perspectives for the systematic TCM treatment of PCOS-associated hyperandrogenemia.关键词
多囊卵巢综合征/高雄激素血症/三阴辨证/《伤寒论》/经方论治Key words
polycystic ovary syndrome/hyperandrogenism/three-yin pattern differentiation/Shang Han Lun(Treatise on Cold Damage)/classical formula treatment分类
医药卫生引用本文复制引用
魏道明,莫蕙..《伤寒论》三阴辨证视角下多囊卵巢综合征高雄激素血症病机与方药研究进展[J].湖南中医药大学学报,2026,46(6):1297-1302,6.基金项目
澳门基金会专用项目(I00669-2508-560). （I00669-2508-560）
