化学工程2026，Vol.54Issue(6)：47-51,5.DOI:10.3969/j.issn.1005-9954.2026.06.008
热敏/高黏性的含盐氰乙酸连续蒸发装备研发应用
Research and application of continuous evaporation equipment for thermosensitive/high-viscosity salt-containing cyanoacetic acid
摘要
Abstract
Aiming at the technological challenges of evaporation and concentration of heat-sensitive materials in the pharmaceutical and fine chemical industries,a continuous small-scale experimental platform was established using a horizontal thin-film evaporator with a solution of cyanoacetic acid as the research object.The effects of temperature(80-150℃)and feed rate(40-80 mL/min)on the dehydration efficiency and product purity were systematically investigated.The experiments demonstrate that 130 ℃ is a critical threshold for controlling the moisture mass fraction(≤1.5％)and purity(mass fraction＞90％)of product.Below this temperature,the dehydration rate increases significantly with rising temperature,but the rate of moisture reduction slows down beyond this point.Within the range of 130-150 ℃,a feed rate of 60 mL/min is found to be the optimal parameter,as it ensures stable liquid film distribution and sufficient thermal load,effectively suppressing hydrolysis side reactions.The technical suitability of horizontal equipment is verified for handling heat-sensitive materials,crucial data support is provided for the selection of industrial continuous evaporation equipment and process optimization.关键词
薄膜蒸发器/含盐氰乙酸/热敏高黏/连续蒸发Key words
film evaporator/sodium cyanoacetate/heat sensitivity/evaporation dehydration分类
化学化工引用本文复制引用
吴茂骞,蒋文才,邢云松,张俊梅,徐畅,蒋镇阳,段振亚..热敏/高黏性的含盐氰乙酸连续蒸发装备研发应用[J].化学工程,2026,54(6):47-51,5.基金项目
山东省自然科学基金资助项目(ZR2024MB134) （ZR2024MB134）
日照市重点研发计划(2024ZDYF010052) （2024ZDYF010052）
