基础医学与临床2026,Vol.46Issue(7):1014-1018,5.DOI:10.16352/j.issn.1001-6325.2026.07.1014
鸢尾素在2型糖尿病及慢性心力衰竭中的作用机制
Mechanism of irisin effect in type 2 diabetes mellitus and chronic heart failure
杨雪 1程晓亮1
作者信息
- 1. 昆明医科大学第二附属医院 老年医学科,云南 昆明 650101
- 折叠
摘要
Abstract
Type 2 diabetes mellitus(T2DM)is closely related to chronic heart failure in the view point of patho-physiological mechanism.Research has shown that irisin as a muscle factor induced by exercise,is widely distribu-ted in human body,which may improve blood glucose threshold of T2DM through a mechanism of reducing insulin resistance,regulating glucose and lipid metabolism,protecting beta cell function,and enhancing cardiac stem cell proliferation and angiogenesis,improving cardiac pathological remodeling,reducing cell apoptosis and so to protect and improve cardiac function.关键词
鸢尾素/2型糖尿病/慢性心力衰竭Key words
irisin/type 2 diabetes mellitus/chronic heart failure分类
医药卫生引用本文复制引用
杨雪,程晓亮..鸢尾素在2型糖尿病及慢性心力衰竭中的作用机制[J].基础医学与临床,2026,46(7):1014-1018,5.