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鸢尾素在2型糖尿病及慢性心力衰竭中的作用机制

杨雪 程晓亮

基础医学与临床2026,Vol.46Issue(7):1014-1018,5.
基础医学与临床2026,Vol.46Issue(7):1014-1018,5.DOI:10.16352/j.issn.1001-6325.2026.07.1014

鸢尾素在2型糖尿病及慢性心力衰竭中的作用机制

Mechanism of irisin effect in type 2 diabetes mellitus and chronic heart failure

杨雪 1程晓亮1

作者信息

  • 1. 昆明医科大学第二附属医院 老年医学科,云南 昆明 650101
  • 折叠

摘要

Abstract

Type 2 diabetes mellitus(T2DM)is closely related to chronic heart failure in the view point of patho-physiological mechanism.Research has shown that irisin as a muscle factor induced by exercise,is widely distribu-ted in human body,which may improve blood glucose threshold of T2DM through a mechanism of reducing insulin resistance,regulating glucose and lipid metabolism,protecting beta cell function,and enhancing cardiac stem cell proliferation and angiogenesis,improving cardiac pathological remodeling,reducing cell apoptosis and so to protect and improve cardiac function.

关键词

鸢尾素/2型糖尿病/慢性心力衰竭

Key words

irisin/type 2 diabetes mellitus/chronic heart failure

分类

医药卫生

引用本文复制引用

杨雪,程晓亮..鸢尾素在2型糖尿病及慢性心力衰竭中的作用机制[J].基础医学与临床,2026,46(7):1014-1018,5.

基础医学与临床

1001-6325

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