中国当代医药2026，Vol.33Issue(14)：39-43,5.DOI:10.3969/j.issn.1674-4721.2026.14.09
鼻负压置换联合雾化治疗儿童肺炎的效果分析及对痰培养转阴影响
Analysis of the effect of nasal negative pressure replacement combined with inhalation therapy in the treatment of pediatric pneumonia and its influence on the negative conversion of sputum culture
摘要
Abstract
Objective To analyze the effect of nasal negative pressure replacement combined with inhalation therapy in the treatment of pediatric pneumonia,and to explore its influence on the negative conversion of sputum culture.Methods A total of 136 patients with pediatric pneumonia admitted to the Affiliated Hospital of Putian University from March to December 2024 were selected as the research objects.According to the random number table method,they were divided into the reference group(68 cases)and the experimental group(68 cases).All children were treated with anti-infection and expectoration.The reference group was treated with inhalation therapy at the same time,and the experimental group was treated with negative pressure replacement on the basis of the reference group.The clinical efficacy,sputum culture negative conversion,clinical symptoms,inflammatory indicators,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score,and clinical pulmonary infection score were compared between the two groups.Results The total effective rate of treatment and negative conversion rate of sputum culture in the experimental group were higher than those in the reference group,and the differences were statistically significant(P＜0.05).The recovery time of fever,cough and runny nose symp-toms and the length of hospital stay in the experimental group were shorter than those in the reference group,and the differences were statistically significant(P＜0.05).After treatment,the white blood cell count(WBC)and C-reactive protein(CRP)levels of the experimental group were lower than those of the reference group,and the differences were statistically significant(P＜0.05).After treatment,the APACHE Ⅱ score and clinical pulmonary infection score of the experimental group were lower than those of the reference group,and the differences were statistically significant(P＜0.05).Conclusion On the basis of anti-infection treatment for pediatric pneumonia,nasal negative pressure replacement combined with inhalation therapy can achieve better results,effectively improve the negative conversion rate of sputum culture,relieve symptoms and reduce inflammatory indicators as soon as possible,which is worthy of application.关键词
鼻负压置换/雾化治疗/儿童肺炎/痰培养转阴Key words
Nasal negative pressure replacement/Inha-lation therapy/Pediatric pneumonia/Negative conversion of sputum culture分类
医药卫生引用本文复制引用
林东,郑立娴..鼻负压置换联合雾化治疗儿童肺炎的效果分析及对痰培养转阴影响[J].中国当代医药,2026,33(14):39-43,5.基金项目
福建省莆田市科技计划项目(2024SJYL082). （2024SJYL082）
